GDC-0349

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Names

[ CAS No. ]:
1207360-89-1

[ Name ]:
GDC-0349

[Synonym ]:
(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea
Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]-
GDC-0349||GDC0349
1-Ethyl-3-(4-{4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl}phenyl)urea
GDC-0349

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
571.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H32N6O3

[ Molecular Weight ]:
452.549

[ Flash Point ]:
299.3±30.1 °C

[ Exact Mass ]:
452.253601

[ PSA ]:
95.34000

[ LogP ]:
1.04

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.620

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Oxetanone
  • (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea

DownStream

Related Compounds

  • gdc-0349
  • GDC-0853
  • GDC-2394
  • GDC-0134
  • GDC-0068
  • GDC-4379
  • 2-Bromo-1-(5-bromopyridin-2-yl)ethanone hydrobromide
  • 1-[1-(3-Chloro-2-methoxyphenyl)cyclopropyl]cyclopropan-1-amine
  • 1-(3-Bromophenyl)cyclobutanecarbaldehyde
  • 1-Bromo-8-(naphthalen-1-yl)pyrene
  • 4-Chloro-6-fluoroquinazolin-2-amine
  • 2,6-Dichloro-9-[2-(oxan-2-yloxy)ethyl]purine
  • 3-(Aminomethyl)-2,9-dimethyl-7H-furo[3,2-g][1]benzopyran-7-one
  • 3-Bromo-2-(2-bromoethyl)thiophene
  • 2-(3-Bromophenyl)pyrrolidin-3-amine
  • O-{[1-(2-bromophenyl)cyclopropyl]methyl}hydroxylamine
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