GDC-0349

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Names

[ CAS No. ]:
1207360-89-1

[ Name ]:
GDC-0349

[Synonym ]:
(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea
Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]-
GDC-0349||GDC0349
1-Ethyl-3-(4-{4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl}phenyl)urea
GDC-0349

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
571.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H32N6O3

[ Molecular Weight ]:
452.549

[ Flash Point ]:
299.3±30.1 °C

[ Exact Mass ]:
452.253601

[ PSA ]:
95.34000

[ LogP ]:
1.04

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.620

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Oxetanone
  • (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea

DownStream

Related Compounds

  • gdc-0349
  • GDC-0853
  • GDC-2394
  • GDC-0134
  • GDC-0068
  • GDC-4379
  • 2-(Methoxy-d3)pyridin-4-amine
  • 2-Chloro-6-[3-[[3-(trimethylsilyl)-3-buten-1-yl]oxy]-1H-pyrazol-1-yl]-3-pyridinecarboxylic acid ethyl ester
  • tert-butyl N-{[3-(difluoromethyl)-3-hydroxycyclobutyl]methyl}carbamate
  • tert-butyl N-{[3-hydroxy-3-(trifluoromethyl)cyclobutyl]methyl}carbamate
  • 2-Chloro-1-(4-cyclopropylphenyl)ethanone
  • Propargyl PEG4 NHS carbonate
  • DNP-PEG3-CH2 acid
  • Fmoc-Dab(Ac)-OH
  • Rel-(3AS,7AS)-4-(tert-butoxycarbonyl)octahydrofuro[3,2-B]pyridine-6-carboxylic acid
  • (3AR,8AR)-Benzyl 8-oxo-3,3A,8,8A-tetrahydroindeno[1,2-C]pyrrole-2(1H)-carboxylate
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