GDC-0349

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Names

[ CAS No. ]:
1207360-89-1

[ Name ]:
GDC-0349

[Synonym ]:
(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea
Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]-
GDC-0349||GDC0349
1-Ethyl-3-(4-{4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl}phenyl)urea
GDC-0349

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
571.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H32N6O3

[ Molecular Weight ]:
452.549

[ Flash Point ]:
299.3±30.1 °C

[ Exact Mass ]:
452.253601

[ PSA ]:
95.34000

[ LogP ]:
1.04

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.620

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-Oxetanone
  • (S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea

DownStream

Related Compounds

  • gdc-0349
  • GDC-0853
  • GDC-2394
  • GDC-0134
  • GDC-0068
  • GDC-4379
  • 4-(3-Oxo-3-(m-tolyl)prop-1-en-1-yl)benzoic acid
  • 5-Bromo-3-fluoropicolinic acid hydrochloride
  • 5-chloro-N-(2,4-dimethoxypyrimidin-5-yl)-2-methoxybenzamide
  • 1-(2,4-Dimethoxypyrimidin-5-yl)-3-(2-methoxyphenyl)urea
  • N-(2,4-dimethoxypyrimidin-5-yl)-3-methylbenzenesulfonamide
  • Ethyl 2-[[2-[[4-[(1,5-dimethyl-1H-pyrazol-4-yl)methylene]-1-ethyl-4,5-dihydro-5-oxo-1H-imidazol-2-yl]thio]acetyl]amino]-6-ethyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
  • 2-chloro-N-(2,4-diethoxypyrimidin-5-yl)-6-fluorobenzamide
  • N-(2,4-diethoxypyrimidin-5-yl)-2-(4-methoxyphenyl)acetamide
  • N-(2,4-diethoxypyrimidin-5-yl)cyclopropanecarboxamide
  • 1-(3-Chloro-4-methylphenyl)-3-[4-(dimethylamino)-2-methoxypyrimidin-5-yl]urea
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