PF-4942847

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Names

[ CAS No. ]:
1207961-33-8

[ Name ]:
PF-4942847

[Synonym ]:
2-Amino-4-(4-chloro-2-(2-(4-fluoro-1H-pyrazol-1-yl)ethoxy)-6-methylphenyl)-N-(2,2-difluoropropyl)-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxamide
2-Amino-4-[4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl]-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide
2-amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid (2,2-difluoropropyl)amide

Chemical & Physical Properties

[ Molecular Formula ]:
C22H23ClF3N7O2

[ Molecular Weight ]:
509.91200

[ Exact Mass ]:
509.15500

[ PSA ]:
111.19000

[ LogP ]:
4.69260

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • imidazole-1-carboxylic acid (2,2-difluoro-propyl)-amide
  • 4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-ylamine
  • 5-Chloro-2-iodo-1-methyl-3-nitrobenzene
  • 5-Chloro-2-iodo-3-methylaniline
  • 5-Chloro-2-iodo-3-methylphenol
  • 2-(4-Chloro-2-Methoxy-6-Methyl-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
  • 2-amino-4-iodo-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
  • 2-amino-4-(4-chloro-2-hydroxy-6-methylphenyl)-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
  • 2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
  • (4-chloro-2-hydroxy-6-methylphenyl)boronic acid

DownStream

Related Compounds

  • PF-4942847
  • PF-06471553
  • PF-05085727
  • PF-03463275
  • PF-06815189
  • PF-06869206
  • {1-[(6-Methoxypyridin-2-yl)methyl]cyclopropyl}methanol
  • 1-[3-(Methoxymethyl)furan-2-yl]cyclohexane-1-carboxylic acid
  • 2-(3-Aminopropoxy)-5-methoxyphenol
  • 1-[3-(Methoxymethyl)furan-2-yl]cyclopropan-1-amine
  • {1-[3-(Methoxymethyl)furan-2-yl]cyclopropyl}methanamine
  • (2-Methoxyphenyl)methyl sulfamate
  • (3S)-4,4-difluoro-3-hydroxypentanoic acid
  • 3-(6-Methoxypyridin-2-yl)but-3-en-1-amine
  • 3-[2-(1-Ethynylcyclopropyl)ethyl]thiophene
  • 4-(3,4-dihydro-2H-pyran-5-yl)-1H-pyrazole
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