PF-4942847

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Names

[ CAS No. ]:
1207961-33-8

[ Name ]:
PF-4942847

[Synonym ]:
2-Amino-4-(4-chloro-2-(2-(4-fluoro-1H-pyrazol-1-yl)ethoxy)-6-methylphenyl)-N-(2,2-difluoropropyl)-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxamide
2-Amino-4-[4-chloro-2-[2-(4-fluoro-1H-pyrazol-1-yl)ethoxy]-6-methylphenyl]-N-(2,2-difluoropropyl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxamide
2-amino-4-{4-chloro-2-[2-(4-fluoropyrazol-1-yl)ethoxy]-6-methylphenyl}-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid (2,2-difluoropropyl)amide

Chemical & Physical Properties

[ Molecular Formula ]:
C22H23ClF3N7O2

[ Molecular Weight ]:
509.91200

[ Exact Mass ]:
509.15500

[ PSA ]:
111.19000

[ LogP ]:
4.69260

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • imidazole-1-carboxylic acid (2,2-difluoro-propyl)-amide
  • 4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-ylamine
  • 5-Chloro-2-iodo-1-methyl-3-nitrobenzene
  • 5-Chloro-2-iodo-3-methylaniline
  • 5-Chloro-2-iodo-3-methylphenol
  • 2-(4-Chloro-2-Methoxy-6-Methyl-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
  • 2-amino-4-iodo-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
  • 2-amino-4-(4-chloro-2-hydroxy-6-methylphenyl)-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
  • 2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
  • (4-chloro-2-hydroxy-6-methylphenyl)boronic acid

DownStream

Related Compounds

  • PF-4942847
  • PF-06471553
  • PF-05085727
  • PF-03463275
  • PF-06815189
  • PF-06869206
  • 8-Benzyl-2-oxo-8-azabicyclo[3.2.1]oct-3-ene-6-carbonitrile
  • 4'-(Trifluoromethyl)flavone
  • 5-nitro-1H-indole-3-sulfonyl chloride
  • 5-nitro-1H-indole-3-sulfonamide
  • 7-nitro-1H-indole-3-sulfonamide
  • 5-Methyl-1-(tert-butyloxycarbonyl)pyrrolidine-2-one
  • Tert-butyl 4-methyl-2-oxopiperidine-1-carboxylate
  • (S)-tert-butyl 2-methyl-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate
  • 3-[4-(1,1-Dimethylethyl)-1-cyclohexen-1-yl]-4-(1-methylethoxy)-3-cyclobutene-1,2-dione
  • 4-(4-Oxo-piperidino)-6,7-dimethoxyquinazoline
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