2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester

Names

[ CAS No. ]:
1207961-61-2

[ Name ]:
2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester

Chemical & Physical Properties

[ Molecular Formula ]:
C23H26ClFN6O3

[ Molecular Weight ]:
488.94200

[ Exact Mass ]:
488.17400

[ PSA ]:
108.39000

[ LogP ]:
4.87200

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methanesulfonic acid 2-(4-fluoropyrazol-1-yl)ethyl ester
  • 2-amino-4-(4-chloro-2-hydroxy-6-methylphenyl)-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
  • 2-(4-Chloro-2-Methoxy-6-Methyl-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane

DownStream

  • PF-4942847
  • 4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidin-2-ylamine

Related Compounds

  • tert-butyl N-[5-(oxiran-2-yl)pentan-2-yl]carbamate
  • 3-(5-Chloro-1,2,5,6-tetrahydropyridin-3-yl)-4-methoxypyridine
  • 3-Bromo-7-methoxypyrazolo[1,5-a]pyridine-2-carboxylic acid
  • 2-(5-Methylthiophen-2-yl)morpholine hydrochloride
  • 3,7-Dibromopyrazolo[1,5-a]pyridine-2-carboxylic acid
  • 4-{[(2R)-pyrrolidin-2-yl]methyl}pyridine dihydrochloride
  • 2-ethoxy-4-[2-(3-methyl-3H-diazirin-3-yl)ethyl]phenol
  • rac-(3R,4R)-1-acetyl-3,4-dimethylpyrrolidine-3-carboxylic acid
  • 5-(2,4-Dimethylphenyl)pyridine-2-carbaldehyde
  • ethyl 2-amino-3-(4-methoxy-1H-pyrazol-1-yl)propanoate
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