Horner-Emmons reagent

Names

[ CAS No. ]:
120943-70-6

[ Name ]:
Horner-Emmons reagent

[Synonym ]:
.dimethyl [2-(tert-butyldimethylsilyl)-2-oxoethyl]-phosphonate
.(MeO)2P(O)CH2COTBS
dimethyl <2-(tert-butyldimethylsilyl)-2-oxoethyl>-phosphonate
.dimethyl 2-(tert-butyldimethylsilyl)-2-oxoethylphosphonate

Chemical & Physical Properties

[ Molecular Formula ]:
C10H23O4PSi

[ Molecular Weight ]:
266.34600

[ Exact Mass ]:
266.11000

[ PSA ]:
62.41000

[ LogP ]:
3.08910

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-bromo-1-tert-butyldimethylsilyl-1-ethanone

DownStream

  • 1-[tert-butyl(dimethyl)silyl]-4,4-dimethylpent-2-en-1-one
  • 1-[tert-butyl(dimethyl)silyl]-4-methylpent-2-en-1-one

Related Compounds

  • slap hydropyridopyrazine reagent
  • ZINC ISOPROPYLSULFINATE
  • p-Dioxane, Reagent
  • bolton-hunter reagent, [125i]
  • Denny-Jaffe reagent
  • DOTAP Transfection Reagent