Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-

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Names

[ CAS No. ]:
121-28-8

[ Name ]:
Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-

[Synonym ]:
Isoproterenon
N-Isopropylnoradrenalone
EINECS 204-461-0
Aludrone
Isoproterenone

Chemical & Physical Properties

[ Density]:
1.185g/cm3

[ Boiling Point ]:
409.7ºC at 760mmHg

[ Melting Point ]:
96ºC

[ Molecular Formula ]:
C11H15NO3

[ Molecular Weight ]:
209.24200

[ Flash Point ]:
201.6ºC

[ Exact Mass ]:
209.10500

[ PSA ]:
69.56000

[ LogP ]:
1.66940

[ Vapour Pressure ]:
2.69E-07mmHg at 25°C

[ Index of Refraction ]:
1.564

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AM7709000
CHEMICAL NAME :
Acetophenone, 3',4'-dihydroxy-2-(isopropylamino)-
CAS REGISTRY NUMBER :
121-28-8
BEILSTEIN REFERENCE NO. :
2105828
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H15-N-O3
MOLECULAR WEIGHT :
209.27
WISWESSER LINE NOTATION :
QR BQ DV1MY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
215 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 226,493,1955

Safety Information

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-chloro-3',4'-dihydroxyacetophenone
  • isopropylamine
  • 3-methoxy-4-hydroxyphenylglyoxal
  • 3,4-dihydroxyphenylglyoxal

DownStream

  • [4-[1-hydroxy-2-(propan-2-ylamino)ethyl]-2-(4-methylbenzoyl)oxyphenyl] 4-methylbenzoate

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%