4-Amino-6-chlorobenzene-1,3-disulfonamide

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Names

[ CAS No. ]:
121-30-2

[ Name ]:
4-Amino-6-chlorobenzene-1,3-disulfonamide

[Synonym ]:
Salmid
Idorese
1-amino-3-chloro-4,6-benzenedisulfonamide
3-chloroanilino-4,6-disulphonamide
1,3-Benzenedisulfonamide, 4-amino-6-chloro-
5-Chloro-2,4-disulfamoylaniline
5-Chloro-2,4-bis(sulfonamide)aniline
2,4-disulfamoyl-5-chloroaniline
Chloraminophenamide
Chloroaminophenamide
4-Amino-6-chlorobenzene-1,3-disulfonamide
4-Amino-6-Chloro-1,3-Benzendisulfonamide
MFCD00007933
5(3)-Chloroaniline-2,4(4,6)-disulfonamide
4-Amino-6-chloro-1,3-benzenedisulfonamide
5-Chloro-2,4-bis(sulfonamido)aniline
4-Amino-6-chloro-benzene-1,3-disulfonic acid diamide
5-chloroaniline-2,4-disulfonamide
EINECS 204-463-1
4-Amino-6-chlorbenzol-1,3-disulfonamid
2-amino-4-chloro-5-sulfamoylbenzenesulfonamide
5-Chloro-2,4-disulfamylaniline
6-amino-4-chlorobenzene-1,3-disulfonamide
Hydrochlorothiazide Impurity 3

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
614.4±65.0 °C at 760 mmHg

[ Melting Point ]:
257-261 °C(lit.)

[ Molecular Formula ]:
C6H8ClN3O4S2

[ Molecular Weight ]:
285.728

[ Flash Point ]:
325.4±34.3 °C

[ Exact Mass ]:
284.964478

[ PSA ]:
163.10000

[ LogP ]:
0.14

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.666

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R23/24;R33

[ Safety Phrases ]:
S28-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Amino-6-chlorobenzene-1,3-di(sulphonyl chloride)
  • 3-Chloroaniline
  • Trichlormethiazide
  • 6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
  • Hydrochlorothiazide

DownStream

  • bemetizide
  • 2,5'-dichloro-2',4'-disulphamoylacetanilide
  • Cyclothiazide
  • cyclopenthiazide
  • Chlorothiazide
  • Hydrochlorothiazide
  • hydrobentizide
  • 6-chloro-3-[(4-fluorophenyl)methyl]-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
  • Methyclothiazide
  • Trichlormethiazide

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.

Bioorg. Med. Chem. Lett. 16 , 2182-8, (2006)

A library of sulfonamides/sulfamates has been investigated for the inhibition of the carboxyterminal truncated form of the alpha-carbonic anhydrase (CA, EC 4.2.1.1) isolated from the gastric pathogen ...

Mass spectrometric behavior of thiazide-based diuretics after electrospray ionization and collision-induced dissociation.

Anal. Chem. 74(15) , 3802-8, (2002)

The mass spectrometric behavior of 21 thiazide-based compounds after electrospray ionization in the negative ion mode and collision-induced dissociation was investigated on a triple-stage quadrupole m...

Detection of urinary markers for thiazide diuretics after oral administration of hydrochlorothiazide and altizide-relevance to doping control analysis

J. Chromatogr. A. 1216(12) , 2466-73, (2009)

In sports, thiazide diuretics are used to flush out previously taken prohibited substances with forced diuresis and in sports where weight classes are involved to achieve acute weight loss. Thiazide d...


More Articles

Related Compounds

  • 4-Amino-6-chlorobenzene-1,3-di(sulphonyl chloride)
  • 4-amino-6-methylbenzene-1,3-disulfonamide
  • 4-amino-6-cyclohexylbenzene-1,3-disulfonamide
  • 4-amino-6-hydroxybenzene-1,3-disulfonamide
  • 4-amino-6-chloro-5-methyl-benzene-1,3-disulfonamide
  • 4-amino-6-(1,1,2,2,2-pentafluoroethyl)benzene-1,3-disulfonamide