Ethyl vanillin
Suppliers
Names
[ CAS No. ]:
121-32-4
[ Name ]:
Ethyl vanillin
[Synonym ]:
burbonal
FEMA 2464
vanirome
EINECS 204-464-7
Bourbonal
3-Ethoxy-4-hydroxybenzaldehyde,Ethylvanillin
Vanilal
VANILLAL
ETHOVAN
3-ethoxy
VHR DQ CO2
ethylvanillin
4-hydroxy-3-ethoxybenzaldehyde
4-OH-3-OEtC6H3CHO
Vanirom
3-Ethoxy-4-hydroxybenzaldehyde
Vanbeenol
MFCD00006944
Ethyl Vanillin
Benzaldehyde, 3-ethoxy-4-hydroxy-
Ethavan
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
295.1±20.0 °C at 760 mmHg
[ Melting Point ]:
76 °C
[ Molecular Formula ]:
C9H10O3
[ Molecular Weight ]:
166.174
[ Flash Point ]:
119.0±15.3 °C
[ Exact Mass ]:
166.062988
[ PSA ]:
46.53000
[ LogP ]:
1.72
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.574
[ Water Solubility ]:
slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CU6125000
- CHEMICAL NAME :
- Benzaldehyde, 3-ethoxy-4-hydroxy-
- CAS REGISTRY NUMBER :
- 121-32-4
- BEILSTEIN REFERENCE NO. :
- 1073761
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 16
- MOLECULAR FORMULA :
- C9-H10-O3
- MOLECULAR WEIGHT :
- 166.19
- WISWESSER LINE NOTATION :
- VHR DQ CO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Human
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1590 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 760 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >7940 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1140 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4480 mg/kg/70D-I
- TOXIC EFFECTS :
- Cardiac - other changes Blood - changes in spleen Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Fibroblast
- DOSE/DURATION :
- 250 mg/L
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,623,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4743 No. of Facilities: 26 (estimated) No. of Industries: 2 No. of Occupations: 17 No. of Employees: 2343 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4743 No. of Facilities: 2917 (estimated) No. of Industries: 20 No. of Occupations: 42 No. of Employees: 53949 (estimated) No. of Female Employees: 31080 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
CU6125000
[ Packaging Group ]:
I; II; III
[ HS Code ]:
2912420000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2912420000
[ Summary ]:
2912420000 3-ethoxy-4-hydroxybenzaldehyde。Supervision conditions:None。VAT:17.0%。Tax rebate rate:13.0%。Lowest tariff:5.5%。General tariff:30.0%
Articles
Zhong Yao Cai 33(4) , 545-6, (2010)
To study the chemical constituents from the marine sponge Iotrochota sp.The compounds were isolated and purified by various column chromatography methods, and their structure wer identified cholestero...
J. Food Sci. 77(9) , M523-7, (2012)
The thermal tolerance Cronobacter sakazakii was examined in sterile powdered infant formula (PIF) rehydrated at 58 °C in water or apple juice supplemented with vanillin, ethyl vanillin, or vanillic ac...
J. Nat. Prod. 71 , 1016-21, (2008)
Four new compounds, including two new dihydroagarofuranoid sesquiterpenes, 8-benzoyloxymutangin (1) and 15-acetoxyorbiculin G (2), a new lignan derivative, 9,9'- O-di-(Z)-feruloyl-(-)-secoisolaricires...