Trimethyl borate

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Names

[ CAS No. ]:
121-43-7

[ Name ]:
Trimethyl borate

[Synonym ]:
Trimthyl borate
BORON METHOXIDE
EINECS 204-468-9
Methyl Borate
B(OCH3)3
TRIMETHYL BORATE FOR SYNTHESIS
Trimethyl borate
boric acid trimethyl ester
trimethyl boronate
Boric acid (HBO), trimethyl ester
trimethyl
trimethoxyborane
THALLIUM HYDROTRIS[3-(2-PYRIDYL)PYRAZOL-1-YL]BORATE
Trimethylborate
Borester O
Boric acid trimethyl ester,Methyl borate
Trimethoxyboron
C3H9BO3
MFCD00008346

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
67.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-34 °C

[ Molecular Formula ]:
C₃H₉BO₃

[ Molecular Weight ]:
103.913

[ Flash Point ]:
-8.3±0.0 °C

[ Exact Mass ]:
104.064476

[ PSA ]:
27.69000

[ LogP ]:
1.45

[ Vapour density ]:
3.59 (vs air)

[ Vapour Pressure ]:
157.1±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.335

[ Stability ]:
Stable. Incompatible with oxidizing agents. Decomposes slowly in the presence of moisture, rapidly in water. Flammable.

[ Water Solubility ]:
reacts

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ED5600000

CHEMICAL NAME :: Boric acid, trimethyl ester

CAS REGISTRY NUMBER :: 121-43-7

BEILSTEIN REFERENCE NO. :: 1697939

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C3-H9-B-O3

MOLECULAR WEIGHT :: 103.93

WISWESSER LINE NOTATION :: 1OBO1&O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964 Volume(issue)/page/year: -,693,1964

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964 Volume(issue)/page/year: -,693,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1290 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964 Volume(issue)/page/year: -,693,1964

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964 Volume(issue)/page/year: -,693,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1980 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 14KTAK "Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964 Volume(issue)/page/year: -,693,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 74430 No. of Facilities: 50 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 1090 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 74430 No. of Facilities: 192 (estimated) No. of Industries: 7 No. of Occupations: 7 No. of Employees: 4878 (estimated) No. of Female Employees: 369 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H312-H319-H360FD-H370

[ Precautionary Statements ]:
P201-P210-P260-P302 + P352 + P312-P308 + P311-P337 + P313

[ Target Organs ]:
Central nervous system, Eyes

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;Xn:Harmful;

[ Risk Phrases ]:
R11;R21

[ Safety Phrases ]:
S16-S27-S36/37/39-S45-S25-S23-S2

[ RIDADR ]:
UN 2416 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
ED5600000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2920909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Methanol
Boric acid
Dimethyl malate
Dimethyl (4-methylphenyl)boronate
Pentaborane(9),1-iodo-
(1S,6R)-diethyl 5-oxo-3-oxabicyclo[4.1.0]heptane-7,7-dicarboxylate
1-bromo-pentaborane(9)
boron,S-(diphenylphosphanylmethyl) ethanethioate
(2-biphenyl)dicyclohexylphosphane-borane(1:1)

DownStream

3,5-di(pyridin-2-yl)phenylboronic acid
2,2,3,4,4,4-HEXAFLUORO-1-BUTANOL
5-PHENYL-2-THIENYLBORONIC ACID
(4'-Bromo-4-biphenylyl)boronic acid
(2,6-DIMETHYL-4-METHOXYPHENYL)BORONIC ACID
2-Fluoro-5-pyridylboronic acid
1,4-benzenediboronic acid
(4-(Thiophen-2-yl)phenyl)boronic acid
2,3,5,6-tetrafluorobenzeneboronic acid
Pentylboronic acid

Customs

[ HS Code ]: 2920909090

[ Summary ]:
2920909090 esters of other inorganic acids of non-metals (excluding esters of hydrogen halides) and their salts; their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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