N-[1-[(2R,3R,4S,5S)-3-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-cyanooxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

Names

[ CAS No. ]:
121055-65-0

[ Name ]:
N-[1-[(2R,3R,4S,5S)-3-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-cyanooxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

[Synonym ]:
N-{4-[(methylsulfonyl)amino]phenyl}acetamide
4-N-acetyl methanesulphonanilide
N-[p-(acetylamino)phenyl]methanesulfonamide

Chemical & Physical Properties

[ Density]:
1.1g/cm3

[ Molecular Formula ]:
C24H42N4O5Si2

[ Molecular Weight ]:
522.78500

[ Exact Mass ]:
522.26900

[ PSA ]:
118.96000

[ LogP ]:
5.30058

[ Index of Refraction ]:
1.518

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Sodium cyanide
  • 4-N-acetyl-1-[2',5'-bis-O-(tert-butyldimethylsilyl)-β-D-erythro-pentofuranos-3'-ulosyl]cytosine

DownStream

  • (2S,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-[tert-butyl(dimethyl)silyl]oxy-2-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolane-3-carbonitrile
  • (2S,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolane-3-carbonitrile