(2S,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-[tert-butyl(dimethyl)silyl]oxy-2-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolane-3-carbonitrile

Names

[ CAS No. ]:
121055-68-3

[ Name ]:
(2S,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-[tert-butyl(dimethyl)silyl]oxy-2-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolane-3-carbonitrile

[Synonym ]:
2',5'-Bis-O-(t-butyldimethylsilyl)-3'-C-cyano-3'-deoxycytidine
2',5'-bis-O-(tert-butyldimethylsilyl)-3'-C-cyano-3'-deoxycytidine
Cytidine,3'-cyano-3'-deoxy-2',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]

Chemical & Physical Properties

[ Density]:
1.1g/cm3

[ Boiling Point ]:
525.7ºC at 760 mmHg

[ Molecular Formula ]:
C22H40N4O4Si2

[ Molecular Weight ]:
480.74800

[ Flash Point ]:
271.8ºC

[ Exact Mass ]:
480.25900

[ PSA ]:
113.38000

[ LogP ]:
4.61728

[ Vapour Pressure ]:
3.82E-11mmHg at 25°C

[ Index of Refraction ]:
1.518

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-[1-[(2R,3R,4S,5S)-3-[tert-butyl(dimethyl)silyl]oxy-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-cyanooxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
  • tert-Butyldimethylsilyl chloride
  • 4-N-acetyl-1-[2',5'-bis-O-(tert-butyldimethylsilyl)-β-D-erythro-pentofuranos-3'-ulosyl]cytosine
  • N-Acetylcytidine

DownStream

  • (2S,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolane-3-carbonitrile

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • tert-butyl N-[1-(2-bromopropyl)cyclobutyl]carbamate
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • (2R)-2-[2-fluoro-3-(trifluoromethyl)phenyl]oxirane
  • 1-(5-bromopyrimidin-2-yl)-N-cyclopropylpiperidine-4-carboxamide
  • Tert-butyl 3-(1-aminocycloheptyl)-3-hydroxypyrrolidine-1-carboxylate
  • 2-bromo-1-[1-(propan-2-yl)-1H-pyrazol-5-yl]ethan-1-ol
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol