(2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

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Names

[ CAS No. ]:
121148-01-4

[ Name ]:
(2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate

[Synonym ]:
cis-4-Amino-1-Boc-2-pyrrolidinecarboxylic acid methyl ester
2-Methyl 1-(2-methyl-2-propanyl) (2R,4R)-4-amino-1,2-pyrrolidinedicarboxylate
1-O-tert-butyl 2-O-methyl (2S,4S)-4-aminopyrrolidine-1,2-dicarboxylate
1,2-Pyrrolidinedicarboxylic acid, 4-amino-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
320.7±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H20N2O4

[ Molecular Weight ]:
244.288

[ Flash Point ]:
147.7±27.9 °C

[ Exact Mass ]:
244.142303

[ PSA ]:
81.86000

[ LogP ]:
0.10

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.490

Safety Information

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-tert-butyl 2-Methyl 4-azidopyrrolidine-1,2-dicarboxylate
  • Boc-Hyp-OMe
  • (2s, 4r)-boc-gamma-mso-proline methyl ester
  • Di-tert-butyl dicarbonate
  • H-Hyp-OMe hydrochloride
  • L-Hydroxyproline
  • BOC-TRANS-4-TOSYLOXY-L-PROLINE METHYL ESTER
  • 4-(S)-azido-(L)-proline methyl ester
  • Boc-Hyp-OH
  • (2S,4R)-METHYL 4-HYDROXYPYRROLIDINE-2-CARBOXYLATE

DownStream

  • (2S,4S)-4-Amino-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) ester

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • (2S,4S)-1-tert-butyl 2-Methyl 4-bromopyrrolidine-1,2-dicarboxylate
  • (2S,4S)-1-tert-butyl 2-methyl 4-methoxypyrrolidine-1,2-dicarboxylate
  • N-t-BOC-trans-4-Fluoro-L-proline methyl ester
  • N-BOC-TRANS-4-IODO-L-PROLINE METHYL ESTER
  • (2R,4R)-1-tert-butyl 2-(2-(9-((2S,5S)-1-((S)-2-(methoxycarbonylamino)-3-methylbutanoyl)-5-methylpyrrolidine-2-carbonyloxy)-8-oxo-8,9,10,11-tetrahydro-5H-dibenzo[c,g]chromen-3-yl)-2-oxoethyl) 4-(methoxymethyl)pyrrolidine-1,2-dicarboxylate
  • METHYL (2S,4S)-1-(TERT-BUTOXYCARBONYL)-4-METHYLPYROGLUTAMATE
  • (2S,4S)-1-tert-Butyl 2-methyl 4-(benzoyloxy)pyrrolidine-1,2-dicarboxylate
  • tert-butyl N-[1-(3-aminobutyl)cyclopentyl]carbamate
  • tert-butyl N-[1-(2-oxopropyl)cyclohexyl]carbamate
  • tert-butyl N-[1-(3-oxobutyl)cyclohexyl]carbamate
  • tert-butyl N-{1-[(piperidin-4-yl)methyl]cyclohexyl}carbamate
  • tert-butyl N-{1-[2-(piperazin-1-yl)ethyl]cyclohexyl}carbamate
  • tert-butyl N-{1-[(piperidin-3-yl)methyl]cyclohexyl}carbamate
  • tert-butyl N-{1-[(pyrrolidin-3-yl)methyl]cyclohexyl}carbamate
  • tert-butyl N-{1-[2-(methylamino)ethyl]cyclohexyl}carbamate
  • tert-butyl N-[1-(3-aminobutyl)cyclohexyl]carbamate
  • tert-butyl N-[1-(1-hydroxyethyl)cyclopropyl]carbamate
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