(6S,7R,8S,8aR)-(+)-methyl 6,7-bis-(3,4-dimethoxyphenyl)-5-oxoindolizidine-8-carboxylate

Names

[ CAS No. ]:
121194-91-0

[ Name ]:
(6S,7R,8S,8aR)-(+)-methyl 6,7-bis-(3,4-dimethoxyphenyl)-5-oxoindolizidine-8-carboxylate

Chemical & Physical Properties

[ Molecular Formula ]:
C26H31NO7

[ Molecular Weight ]:
469.52700

[ Exact Mass ]:
469.21000

[ PSA ]:
83.53000

[ LogP ]:
3.32010

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2R,4S,5R)-4-(((tert-butyldimethylsilyl)oxy)methyl)-2-phenyl-1,3-dioxan-5-yl (E)-6-((E)-2,3-bis(3,4-dimethoxyphenyl)acrylamido)hex-2-enoate
  • (6R,7R,8S,8aR,2'R,4'S,5'R)-(+)-4'-(t-butyldimethylsiloxymethyl)-2'-phenyl-1',3'-dioxan-5'-yl 6,7-bis-(3,4-dimethoxyphenyl)-5-oxoindolizidine-8-carboxylate

DownStream

  • (13aR,14S)-2,3,6,7-tetramethoxy-9-oxo-9,11,12,13,13a,14-hexahydrodibenzo[f,h]pyrrolo[1,2-b]isoquinoline-14-carboxylic acid
  • (-)-9-oxotylophorine