(Ala1.3.11.15)-Endothelin-1 trifluoroacetate salt

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Names

[ Name ]:
(Ala1.3.11.15)-Endothelin-1 trifluoroacetate salt

[Synonym ]:
asasslmdkeavyfahldiiw
L-Tryptophan, L-alanyl-L-seryl-L-alanyl-L-seryl-L-seryl-L-leucyl-L-methionyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-alanyl-L-histidyl-L-leucyl-L-α-as partyl-L-isoleucyl-L-isoleucyl-
ala-ser-ala-ser-ser-leu-met-asp-lys-glu-ala-val-tyr-phe-ala-his-leu-asp-ile-ile-trp
MFCD00143562
L-Alanyl-L-seryl-L-alanyl-L-seryl-L-seryl-L-leucyl-L-methionyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-alanyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isole ucyl-L-isoleucyl-L-tryptophan
4 ala et-1

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
2391.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀₉H₁₆₃N₂₅O₃₂S

[ Molecular Weight ]:
2367.674

[ Flash Point ]:
1400.1±34.3 °C

[ Exact Mass ]:
2366.161621

[ PSA ]:
933.93000

[ LogP ]:
3.12

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.586

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Alterations in ET-1, not nitric oxide, in 1-week-old lambs with increased pulmonary blood flow.

Am. J. Physiol. Heart Circ. Physiol. 284(2) , H480-90, (2003)

Altered pulmonary vascular reactivity is a source of morbidity and mortality for children with congenital heart disease and increased pulmonary blood flow. Nitric oxide (NO) and endothelin (ET)-1 are ...

Endothelin receptor blockade does not alter the increase in pulmonary blood flow due to oxygen ventilation in fetal lambs.

Pediatr. Res. 40(1) , 152-7, (1996)

At birth, pulmonary vasodilation occurs during rhythmic distension of the lungs with oxygen. Both mechanical and humoral factors are involved, including the release of vasoactive substances such as pr...

Production of monocyte chemoattractant protein-1 and cytokine-induced neutrophil chemoattractant-1 in rat brain is stimulated by intracerebroventricular administration of an endothelin ETB receptor agonist.

Neuroreport 18(12) , 1275-9, (2007)

The role of endothelin (ET)B receptors in chemokine production in the brain of rats was examined. Intracerebroventricular administration of 500 pmol/day of Ala(1,3,11,15)-ET-1, a selective ETB agonist...

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