disodium,[3-(dimethylamino)-1-hydroxy-1-phosphonatopropyl]phosphonic acid

Names

[ CAS No. ]:
121368-58-9

[ Name ]:
disodium,[3-(dimethylamino)-1-hydroxy-1-phosphonatopropyl]phosphonic acid

[Synonym ]:
IG 8801
disodium [3-(dimethylamino)-1-hydroxy-1-phosphonatopropyl]phosphonic acid
Dimethyl APD
Disodium (3-(dimethylamino)-1-hydroxypropylidene)bisphosphate
UNII-G90M9V9GMQ
Phosphoric acid,(3-(dimethylamino)-1-hydroxypropylidene)bis-,disodium salt
Olpadronate sodium

Chemical & Physical Properties

[ Boiling Point ]:
590.1ºC at 760mmHg

[ Molecular Formula ]:
C5H13NNa2O7P2

[ Molecular Weight ]:
307.08600

[ Flash Point ]:
310.7ºC

[ Exact Mass ]:
306.99600

[ PSA ]:
163.81000

[ Vapour Pressure ]:
2.21E-16mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TC2509000
CHEMICAL NAME :
Phosphoric acid, (3-(dimethylamino)-1-hydroxypropylidene)bis-, disodium salt
CAS REGISTRY NUMBER :
121368-58-9
LAST UPDATED :
199603
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H13-N-O7-P2.2Na
MOLECULAR WEIGHT :
307.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
32400 mg/kg/27W-I
TOXIC EFFECTS :
Musculoskeletal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
BONEDL Bone. (Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591) V.6- 1985- Volume(issue)/page/year: 16,285S,1995

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-(2-hydroxy-2-methylpropyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-(But-3-yn-1-ylamino)nicotinic acid
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • [2-Methyl-4-[4-(trifluoromethoxy)phenyl]phenyl]methanol
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde