(E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one
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Names
[ CAS No. ]:
121524-18-3
[ Name ]:
(E)-1-[(2R)-2-(2-hydroxyethyl)piperidin-1-yl]-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)prop-2-en-1-one
[Synonym ]:
2-Piperidineethanol,1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-,(R-(E))
C23H25N3O2
(R-(E))-1-(1-Oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-propenyl)-2-piperidineethanol
FK 453
(+)-(R)-((E)-3-(2-Phenylpyrazolo(1,5-a)pyridin-3-yl)acryloyl)-2-piperidineethanol
Chemical & Physical Properties
[ Density]:
1.21g/cm3
[ Molecular Formula ]:
C23H25N3O2
[ Molecular Weight ]:
375.46400
[ Exact Mass ]:
375.19500
[ PSA ]:
57.84000
[ LogP ]:
3.71590
[ Index of Refraction ]:
1.636
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TM9475500
- CHEMICAL NAME :
- 2-Piperidineethanol, 1-(1-oxo-3-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-2-pr openyl)-, (R-(E))-
- CAS REGISTRY NUMBER :
- 121524-18-3
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C23-H25-N3-O2
- MOLECULAR WEIGHT :
- 375.51
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 46,185,1996