6-bromoflavone

Suppliers

Names

[ CAS No. ]:
1218-80-0

[ Name ]:
6-bromoflavone

[Synonym ]:
6-Bromoflavone
6-bromo-2-phenyl-4H-1-benzopyran-4-one
6-bromo-2-phenyl-chromen-4-one
6-bromo-2-phenyl-4H-chromen-4-one
MFCD00276169
6-Brom-2-phenyl-chromen-4-on

Chemical & Physical Properties

[ Density]:
1.54g/cm3

[ Boiling Point ]:
421.1ºC at 760 mmHg

[ Melting Point ]:
193-196ºC(lit.)

[ Molecular Formula ]:
C15H9BrO2

[ Molecular Weight ]:
301.13500

[ Flash Point ]:
208.5ºC

[ Exact Mass ]:
299.97900

[ PSA ]:
30.21000

[ LogP ]:
4.22250

[ Vapour Pressure ]:
2.67E-07mmHg at 25°C

[ Index of Refraction ]:
1.656

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Phenylacetylene
  • 5-Bromosalicylaldehyde
  • 6-bromoflavanone
  • 1-(5-Bromo-2-hydroxyphenyl)-3-phenyl-1,3-propanedione
  • 2-Propen-1-one,1-(5-bromo-2-hydroxyphenyl)-3-phenyl-
  • 5'-Bromo-2'-hydroxyacetophenone
  • Benzoyl chloride
  • 2-Propen-1-one,1-(3-bromophenyl)-3-phenyl-, (2E)-

DownStream

  • 3,6-dibromo-2-phenylchromen-4-one
  • 2,6-diphenylchromen-4-one
  • benzoic acid

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

6-Bromoflavone, a high affinity ligand for the central benzodiazepine receptors is a member of a family of active flavonoids. Marder M, et al.

Biochem. Biophys. Res. Commun. 223(2) , 384-389, (1996)

Reaction of 2'-hydroxychalcone dibromides with pyridine. Reddy NJ, et al.

J. Org. Chem. 46(3) , 638-641., (1981)


More Articles

Related Compounds

  • 6-isothiocyanato-6-pentylundecane
  • 6-Iodo-3-pyridinamine
  • 6-phenylpyridazine-3-carboxylic acid
  • 6,6,6-trifluoro-5-hydroxy-2,2-dimethyl-5-(trifluoromethyl)hexan-3-one
  • 6,9-Dihydro-7,8-dihydroxy-6,9-dioxo-2-phenazinecarboxylic acid
  • 6-aminoundecanoic acid
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-{[(tert-butoxy)carbonyl]amino}-3-methylthiophene-2-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-{[(benzyloxy)carbonyl]amino}-2-phenylacetate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-{[(benzyloxy)carbonyl]amino}-3-phenylpropanoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-(4-{[(tert-butoxy)carbonyl]amino}phenyl)acetate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-(benzyloxy)-3-methoxybenzoate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-benzyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-benzyl-6-cyclopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-benzyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
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