phenyl acetate

Names

[ CAS No. ]:
122-79-2

[ Name ]:
phenyl acetate

[Synonym ]:
PHENYL ACETATE
MFCD00008699
phenoxyacetoaldehyde
phenyl-acetate
phenol acetate
phenoxyethoxide
Acetic acid phenyl ester
acetoxybenzene
Acetyl phenol
EINECS 204-575-0

Chemical & Physical Properties

[ Density]:
1.073 g/mL at 25 °C(lit.)

[ Boiling Point ]:
196 °C(lit.)

[ Melting Point ]:
195-196℃

[ Molecular Formula ]:
C₈H₈O₂

[ Molecular Weight ]:
136.14800

[ Flash Point ]:
170 °F

[ Exact Mass ]:
136.05200

[ PSA ]:
26.30000

[ LogP ]:
1.61190

[ Vapour Pressure ]:
0.418mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.501(lit.)

[ Stability ]:
Stable. Incompatible with strong acids, strong bases, strong reducing agents, strong oxidizing agents. Combustible.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AJ2800000

CHEMICAL NAME :: Acetic acid, phenyl ester

CAS REGISTRY NUMBER :: 122-79-2

BEILSTEIN REFERENCE NO. :: 0636458

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C8-H8-O2

MOLECULAR WEIGHT :: 136.16

WISWESSER LINE NOTATION :: 1VOR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/4/1964 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1630 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 8 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 11/4/1964

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S36

[ RIDADR ]:
NA 1993 / PGIII

[ WGK Germany ]:
2

[ RTECS ]:
AJ2800000

[ HS Code ]:
2915390090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Acetophenone
acetic acid
Phenol
Acetyl chloride
2-acetyl-4,5-dichloropyridazin-3-one
Ethanoic anhydride
N5-acetyl-DBN*BPh4
vinyl acetate
acetic acid,benzene-1,4-diol,4-methylbenzenesulfonic acid
Trimethyl Phenoxysilane

DownStream

Benzoic acid,2-acetyl-, methyl ester
(2-acetylphenyl) 3-nitrobenzoate
acetyl iodide
Phenyl benzoate
2',4',6'-Trihydroxyacetophenone Monohydrate
2,5-Dihydroxyacetophenone
Phenol,2,4,6-tribromo-, 1-acetate
Resorcinol (monoacetate)
1,2-Benzenediol,1-acetate
4-Acetoxyphenol

Customs

[ HS Code ]: 2915390090

[ Summary ]:
2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%

Articles

Rosiglitazone attenuates atherosclerosis and increases high-density lipoprotein function in atherosclerotic rabbits.

Int. J. Mol. Med. 35(3) , 715-23, (2015)

Rosiglitazone has been found to have anti-atherogenic effects and to increase serum high-density lipoprotein (HDL) cholesterol (HDL-C) levels. However, in vivo studies investigating the regulation of ...

Serum myeloperoxidase/paraoxonase 1 ratio as potential indicator of dysfunctional high-density lipoprotein and risk stratification in coronary artery disease.

Atherosclerosis 234(2) , 288-94, (2014)

Granular leukocyte-derived myeloperoxidase (MPO) promotes oxidation of lipoproteins, while paraoxonase 1 (PON1) has antioxidant properties for high-density lipoprotein (HDL). We evaluated their effect...