P-[[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]methyl]phosphonic acid dimethyl ester

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Names

[ CAS No. ]:
1221497-92-2

[ Name ]:
P-[[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]methyl]phosphonic acid dimethyl ester

[Synonym ]:
dimethyl 2-oxo-3-(m-chlorophenoxy)propylphosphonate
dimethyl [3-(3-chlorophenoxy)-2-oxoprop-1-yl]phosphonate
dimethyl [4-(4-fluorophenyl)-6-isopropyl-2-[methyl (methylsulfonyl) amino]pyrimidine-5-ylmethyl]phosphonate
dimethyl 2-oxo-3-(3-chlorophenoxy)propylphosphonate
dimethyl [3-(3-chlorophenoxy)-2-oxopropyl]-phosphonate

Chemical & Physical Properties

[ Molecular Formula ]:
C18H25FN3O5PS

[ Molecular Weight ]:
445.44500

[ Exact Mass ]:
445.12400

[ PSA ]:
116.88000

[ LogP ]:
4.86860

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N-[5-bromomethyl-4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-methanesulfonamide
  • Trimethyl phosphite
  • 4-(4-fluorophenyl)-6-isopropyl-2-[(n-methyl-n-methylsulfonyl)amino]pyriminl-5-yl-methanol

DownStream

  • tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate

Related Compounds

  • 2-(1-Methylcyclopropyl)cyclopropane-1-carbaldehyde
  • 3,6-Dibromo-2-(methoxymethyl)pyridine
  • (4-Chloro-2-fluoro-6-methylphenyl)methanol
  • 7-[4-[(2-Chloro-6-fluorophenyl)methoxy]-3-methoxyphenyl]-N-(2,4-dimethylphenyl)-1,7-dihydro-5-methyl-2-(propylthio)[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
  • 2-Pyridinecarbonitrile, 3-hydroxy-6-nitro-
  • 4-(Aminomethyl)-2,3-difluorobenzonitrile
  • 2-(Benzylamino)quinolin-7-ol
  • 2-Amino-3-bromo-7-quinolinol
  • 5-(2-Pyridinyl)-8-quinolinol
  • 3-Cyano-4-fluoro-5-iodobenzoic acid