dimethyl n,n-diisopropylphosphoramidite

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Names

[ Name ]:
dimethyl n,n-diisopropylphosphoramidite

[Synonym ]:
DIMETHYL N N-DIISOPROPYLPHOSPHORAMIDITE
N,N-diisopropyl-dimethylphosphoramidite
(DIMETHOXYPHOSPHANYL)BIS(PROPAN-2-YL)AMINE
(dimethoxyphosphanyl)diisopropylamine
dimethoxy-N,N-diisopropylphosphoramidite
DIMETHYL-N,N-DIISOPROPYLPHOSPHORAMIDITE
DIMETHYL-N,N-DIISOPROPYLPHOSPHOROAMIDITE
dimethyl-N,N-diisopropylphosphoramidite
O,O-dimethyl-N,N-diisopropylphosphoramidite

Chemical & Physical Properties

[ Density]:
0.840 g/mL at 20ºC(lit.)

[ Boiling Point ]:
54ºC10 mm Hg(lit.)

[ Molecular Formula ]:
C₈H₂₀NO₂P

[ Molecular Weight ]:
193.22400

[ Flash Point ]:
100ºC

[ Exact Mass ]:
193.12300

[ PSA ]:
35.29000

[ LogP ]:
2.62490

[ Index of Refraction ]:
n20/D 1.420(lit.)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Articles

Synthesis and selective cleavage of oligodeoxyribonucleotides containing non-chiral internucleotide phosphoramidate linkages.

Nucleic Acids Res. 17 , 5973, (1989)

Oligodeoxynucleotides containing phosphoramidate internucleotide links 3'-OP(O)NH-5' have been prepared using standard solid phase phosphoramidite techniques. For the incorporation of the phosphoramid...

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