Rosiglitazone

Suppliers

Names

[ Name ]:
Rosiglitazone

[Synonym ]:
2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]- (9CI)
Avandia
5-(4-{2-[Methyl(2-pyridinyl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione
MFCD00871760
5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione
2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-
5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
585.0±35.0 °C at 760 mmHg

[ Melting Point ]:
153-155ºC

[ Molecular Formula ]:
C₁₈H₁₉N₃O₃S

[ Molecular Weight ]:
357.427

[ Flash Point ]:
307.6±25.9 °C

[ Exact Mass ]:
357.114716

[ PSA ]:
96.83000

[ LogP ]:
2.56

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.642

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S45-S28A-S20/21

[ RIDADR ]:
3280

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(5Z)-5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione
5-[4-[2-[N-Methyl-N-(2-pyridinyl)amino]ethoxy]benzylidene]-2,4-thiazolidinedione
5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione
2,4-Thiazolidinedione
4-(2-(METHYL(PYRIDIN-2-YL)AMINO)ETHOXY)BENZALDEHYDE
2-Chloropyridine
2-[Methyl(2-pyridinyl)amino]ethanol
2-Fluoropyridine
4-Hydroxybenzyl alcohol
4-Fluorobenzaldehyde

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Establishment of lipofection for studying miRNA function in human adipocytes.

PLoS ONE 9(5) , e98023, (2014)

miRNA dysregulation has recently been linked to human obesity and its related complications such as type 2 diabetes. In order to study miRNA function in human adipocytes, we aimed for the modulation o...

ADP-ribosylation factor 6 regulates endothelin-1-induced lipolysis in adipocytes.

Biochem. Pharmacol. 90(4) , 406-13, (2014)

Endothelin-1 (ET-1) induces lipolysis in adipocytes, where ET-1 chronic exposure results in insulin resistance (IR) through suppression of glucose transporter (GLUT)4 translocation to the plasma membr...

Preconditioning L6 Muscle Cells with Naringin Ameliorates Oxidative Stress and Increases Glucose Uptake.

PLoS ONE 10 , e0132429, (2015)

Enhanced oxidative stress contributes to pathological changes in diabetes and its complications. Thus, strategies to reduce oxidative stress may alleviate these pathogenic processes. Herein, we have i...

Rosiglitazone-d3
Rosiglitazone HCl
Rosiglitazone maleate
Rosiglitazone cholinate
ROSIGLITAZONE-5-SULFOXY
5-Hydroxy Rosiglitazone
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
1-(Chloromethyl)-2-fluoro-3-methoxy-4-nitrobenzene
Benzenamine, 2,3,4,5,6-pentafluoro-N-(2-methylcyclopropyl)-
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine