desmethyldoxepin

Names

[ CAS No. ]:
1225-56-5

[ Name ]:
desmethyldoxepin

[Synonym ]:
UNII-J7JTC0A5D6
Demethyldoxepin
Nordoxepin
11-<3-Methylamino-propyliden)-6,11-dihydro-dibenzo<b.e>oxepin
Monodesmethyldoxepin
Desmethyldoxepin
N-desmethyl-doxepin

Chemical & Physical Properties

[ Density]:
1.134g/cm3

[ Boiling Point ]:
420.8ºC at 760mmHg

[ Melting Point ]:
63-65℃

[ Molecular Formula ]:
C18H19NO

[ Molecular Weight ]:
265.35000

[ Flash Point ]:
174.5ºC

[ Exact Mass ]:
265.14700

[ PSA ]:
21.26000

[ LogP ]:
4.01110

[ Vapour Pressure ]:
2.74E-07mmHg at 25°C

[ Index of Refraction ]:
1.635

[ Storage condition ]:
?20°C

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H370

[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
11-23/24/25-39/23/24/25

[ Safety Phrases ]:
7-16-36/37-45

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution

[ HS Code ]:
2932999099

Synthetic Route

Precursor & DownStream

Precursor

  • Doxepin hydrochloride

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Determination of perhexiline and its metabolite hydroxyperhexiline in human plasma by liquid chromatography/tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(27) , 3025-30, (2009)

Perhexiline is a drug that is used for treatment of moderate to severe angina pectoris that has not responded to other treatment. It has a low therapeutic index, and saturable metabolism that is also ...

Simultaneous determination of doxepin and nordoxepin in serum using high-performance liquid chromatography.

J. Chromatogr. A. 419 , 445-51, (1987)

Quantitative determination of E- and Z-doxepin and E- and Z-desmethyldoxepin by high-performance liquid chromatography.

Ther. Drug Monit. 17(4) , 371-6, (1995)

A high-performance liquid chromatographic (HPLC) method was developed for the quantitative, simultaneous determination of the following four compounds in serum: E-doxepin, Z-doxepin, E-desmethyldoxepi...


More Articles


Related Compounds

  • N-Desmethyldoxepin
  • Desmethyldoxepin hydrochloride
  • desmethyldoxepin hydrochloride salt
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • methyl {(4Z)-1-(4-methoxyphenyl)-5-oxo-4-[1-(pyridin-3-ylamino)ethylidene]-4,5-dihydro-1H-pyrazol-3-yl}acetate
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1-[(3R)-3-(pyridin-4-yloxy)pyrrolidin-1-yl]prop-2-en-1-one
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine