(dimethyl)[10H-pyrido[3,2-b][1,4]benzothiazine-10-propyl]ammonium chloride

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Names

[ Name ]:
(dimethyl)[10H-pyrido[3,2-b][1,4]benzothiazine-10-propyl]ammonium chloride

[Synonym ]:
(3-Benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propyl)-dimethyl-amin,Monohydrochlorid
Dominal hydrochloride
Dominal forte
(dimethyl)(10H-pyrido[3,2-b][1,4]benzothiazine-10-propyl)ammonium chloride
N,N-dimethyl-10H-pyrido[3,2-b][1,4]benzothiazine-10-propanamine,monohydrochloride
10-(3-Dimethylaminopropyl)-1-azaphenothiazine hydrochloride
Tolnate
Prothipendyl HCl
(3-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propyl)-dimethyl-amine,monohydrochloride
Prothipendyl hydrochloride
Azacon

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₀ClN₃S

[ Molecular Weight ]:
321.86800

[ Exact Mass ]:
321.10700

[ PSA ]:
41.43000

[ LogP ]:
1.15470

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU8750000

CHEMICAL NAME :: 10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(3-(dimethylamino)propyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 1225-65-6

LAST UPDATED :: 199012

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C16-H19-N3-S.Cl-H

MOLECULAR WEIGHT :: 321.90

WISWESSER LINE NOTATION :: T C666 BN DN ISJ B1Y1&N1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 610 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,292,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 115 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,292,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1323 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,292,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 110 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,292,1972

Related Compounds

[1-(Piperidine-4-carbonyl)piperidin-4-yl]methanol
2-[4-(Hydroxymethyl)piperidin-1-yl]benzonitrile
2-(1-((2-Methoxy-5-methylphenyl)sulfonyl)piperidin-3-yl)-5-neopentyl-1,3,4-oxadiazole
2-(4-(Hydroxymethyl)piperidin-1-yl)isonicotinonitrile
5-(4-(hydroxymethyl)piperidine-1-carbonyl)pyridin-2(1H)-one
2-[1-(3-chlorophenyl)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl]acetic acid
1-(2-fluoro-5-methylphenyl)-4-hydroxy-1H-pyrazole-3-carboxylic acid
4-(difluoromethoxy)-1-phenyl-1H-pyrazole-3-carboxylic acid
3-methyl-N-[2-(5-sulfamoylthiophen-2-yl)ethyl]butanamide
2,2-dimethyl-N-[2-(5-sulfamoylthiophen-2-yl)ethyl]propanamide

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