((2S,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methyl benzoate

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Names

[ CAS No. ]:
122567-97-9

[ Name ]:
((2S,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methyl benzoate

[Synonym ]:
5'-Benzoyl-2',3'-dideoxy-2',3'-didehydrothymidine
Stavudine impurity I
5'-O-benzoyl-2',3'-didehydro-3'-deoxythymidine
5'-benzoyl-D4T
Thymidine,2',3'-didehydro-3'-deoxy-,5'-benzoate
((2S,5R)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methyl benzoate

Chemical & Physical Properties

[ Density]:
1.324g/cm3

[ Melting Point ]:
151-153°C

[ Molecular Formula ]:
C17H16N2O5

[ Molecular Weight ]:
328.31900

[ Exact Mass ]:
328.10600

[ PSA ]:
90.65000

[ LogP ]:
1.56790

[ Index of Refraction ]:
1.59

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzoyl chloride
  • Stavudine
  • 2,2'-anhydro-1-(5'-O-benzoyl-3'-O-methylsulfonyl-β-D-lyxofuranosyl)thymine
  • 4-ETHYLOCTANOICACID
  • Sodium Benzoate
  • 5-Methyluridine
  • 1-(2-O-tosyl-3,5-di-O-benzoyl-β-D-xylofuranosyl)thymine

DownStream

  • Stavudine
  • 3'-deoxy-4-thiothymidine
  • 1-[5-(hydroxymethyl)furan-2-yl]-5-methylpyrimidine-2,4-dione
  • N-[2-(4-chlorophenoxy)ethyl]-2-[[6-(1,3-dioxoisoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetamide