N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylimino)methyl)furan-2-yl)quinazolin-4-amine

Names

[ CAS No. ]:
1227853-06-6

[ Name ]:
N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylimino)methyl)furan-2-yl)quinazolin-4-amine

[Synonym ]:
.N-{3-chloro-4-(3-fluorobenzyloxy)phenyl}-6-[5-({(2-methane-sulphonyl)ethylimino}methyl)-2-furyl]-4-quinazolinamine
N-{3-chloro-4-[3-fluorobenzyloxy]phenyl}-6-[5-({[2-methane-sulphonyl-ethyl]imino}methyl)-2-furyl]-4-quinazolinamine
.N-{3-chioro-4-(fluorobenzyloxy) phenyl}-6-[5-({(2-methane-sulphonyl)ethyl imino}methyl)-2-furyl]-4-quinazolinamine

Chemical & Physical Properties

[ Molecular Formula ]:
C29H24ClFN4O4S

[ Molecular Weight ]:
579.04200

[ Exact Mass ]:
578.11900

[ PSA ]:
115.06000

[ LogP ]:
7.62220

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • N(1)-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-N,N-dimethylformamidine

DownStream

  • Lapatinib ditosylate hydrate
  • Lapatinib (GW572016)

Related Compounds

  • 2-(Benzyloxy)-3-chloro-5-fluorobenzaldehyde
  • 2-Chloro-6-iodo-3-methoxybenzaldehyde
  • 1,4-Dichloro-2-ethoxy-3-iodobenzene
  • (2-Bromo-3-ethoxy-6-fluorophenyl)methanol
  • 5-Bromo-N-cyclohexyl-2-fluoro-3-methylbenzamide
  • 3-(Benzyloxy)-4-fluoro-5-methylbenzoic acid
  • 3-(Benzyloxy)-4-fluoro-5-methylbenzaldehyde
  • 4-(Benzyloxy)-5-chloro-2-fluorobenzoic acid
  • (2-Chloro-4-fluoro-3-methoxyphenyl)(pyrrolidin-1-yl)methanone
  • Methyl 2,6-dichloro-3-(trifluoromethyl)benzoate
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