(4R,6R,2E)-methyl 7-hydroxy-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)hept-2-enoate

Names

[ CAS No. ]:
122871-24-3

[ Name ]:
(4R,6R,2E)-methyl 7-hydroxy-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)hept-2-enoate

Chemical & Physical Properties

[ Molecular Formula ]:
C16H32O5Si

[ Molecular Weight ]:
332.50800

[ Exact Mass ]:
332.20200

[ PSA ]:
64.99000

[ LogP ]:
2.82170

Synthetic Route

Precursor & DownStream

Precursor

  • (4R,6R,2E)-methyl 7-(dimethyl-t-butylsiloxy)-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)hept-2-enoate
  • (2R,4R)-5-(dimethyl-t-butylsiloxy)-2,4-dimethylpentane-1,2-diol
  • (2R,4R)-5-(dimethyl-t-butylsiloxy)-2-hydroxy-2,4-dimethylpentanal
  • (4R,6R,2E)-methyl 7-(dimethyl-t-butylsiloxy)-4-hydroxy-4,6-dimethylhept-2-enoate
  • (2E,4R)-ethyl 5-((tert-butyldimethylsilyl)oxy)-2,4-dimethylpent-2-enoate
  • (2S,3S,4S)-5-(dimethyl-t-butylsiloxy)-2,4-dimethyl-2,3-epoxypentan-1-ol

DownStream

  • Cytochalasin H
  • (4S,6S)-methyl 8-hydroxy-4,6-dimethyl-4-(2-trimethylsilylethoxymethoxy)octanoate
  • (4S,6S,8E,10E,12E)-methyl 4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trienoate
  • (4S,6S,8E,10E,12E)-1-(imidazol-1'-yl)-4,6,12-trimethyl-4-(2-trimethylsilylethoxymethoxy)tetradeca-8,10,12-trien-1-one
  • (5S,4'S,6'S,8'E,10'E,12'E)-1-benzoyl-5-benzyl-3-phenylseleno-3-[4',6',12'-trimethyl-4'-(2-trimethylsilylethoxymethoxy)-1'-oxotetradeca-8',10',12'-trienyl]pyrrolidin-2-one
  • (S)-1-benzoyl-5-benzyl-3-((4S,6S,8E,10E,12E)-4,6,12-trimethyl-4-((2-(trimethylsilyl)ethoxy)methoxy)tetradeca-8,10,12-trienoyl)-1H-pyrrol-2(5H)-one
  • (6R,7S,16S,18S)-6,7-epoxy-16,18-dimethyl-10-phenyl-18-(2-trimethylsilylethoxymethoxy)[11]cytochalas-13t-ene-1,21-dione
  • (3S,3aR,4S,6S,6aR,10S,12S,15aR,E)-3-benzyl-4,10,12-trimethyl-5-methylene-6,12-bis((2-(trimethylsilyl)ethoxy)methoxy)-3,3a,4,5,6,6a,9,10,11,12,13,14-dodecahydro-1H-cycloundeca[d]isoindole-1,15(2H)-dione
  • (16S,18S)-16,18-dimethyl-10-phenyl-18-(2-trimethylsilylethoxymethoxy)[11]cytochalasa-6(7),13t-diene-1,21-dione
  • (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-3-benzyl-4,10,12-trimethyl-5-methylene-1-oxo-6,12-bis((2-(trimethylsilyl)ethoxy)methoxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate

Related Compounds

  • Methyl 4-amino-4-(2-chloro-5-fluorophenyl)butanoate
  • 4-[2-(Difluoromethoxy)-3-methylphenyl]-1,3-thiazol-2-amine
  • benzyl N-(1-cyanoethyl)-N-phenylcarbamate
  • 2-(2-amino-1,1-difluoroethyl)-4-fluoro-N,N-dimethylaniline
  • 1-(2,2-Dimethylthiolan-3-yl)-2,2,2-trifluoroethan-1-one
  • 1,1-difluoro-2-(1-methyl-1H-pyrazol-3-yl)propan-2-amine
  • (1S)-2,2,2-trifluoro-1-(2-methyl-2,3-dihydro-1-benzofuran-5-yl)ethan-1-ol
  • 3-(2,2-Dimethylthiolan-3-yl)-1,1,1-trifluoropropan-2-ol
  • 1-(6-chloro-1-methyl-1H-indol-3-yl)-2,2,2-trifluoroethan-1-ol
  • 2-{3-[(Dimethylamino)methyl]-4-hydroxyphenyl}-2,2-difluoroacetic acid
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