(1R,2S,5S)-3-((S)-2-(3-(1-(tert-butylsulfonylmethyl)cyclohexyl)ureido)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Suppliers

Names

[ CAS No. ]:
1229337-32-9

[ Name ]:
(1R,2S,5S)-3-((S)-2-(3-(1-(tert-butylsulfonylmethyl)cyclohexyl)ureido)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxylic acid

Chemical & Physical Properties

[ Molecular Formula ]:
C26H45N3O6S

[ Molecular Weight ]:
527.71700

[ Exact Mass ]:
527.30300

[ PSA ]:
144.75000

[ LogP ]:
4.79810

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methyl cyclohexanoate
  • cyclohexylidenemethoxymethoxy(trimethyl)silane
  • Cyclohexanone
  • tert-butyl methyl sulfide
  • 2-methyl-2-methylsulfonyl-propane
  • N-cyclohexylidene-2-methylpropane-2-sulfinamide
  • 1-((tert-butylsulfonyl)methyl)cyclohexane-1-carboxylic acid
  • 1-((tert-butylsulfonyl)methyl)-1-isocyanatocyclohexane
  • (S)-2-(3-(1-(tert-butylsulfonylmethyl)cyclohexyl)ureido)-3,3-dimethylbutanoic acid

DownStream

  • (1R,2S,5S)-3-[(2S)-2-[[1-(tert-butylsulfonylmethyl)cyclohexyl]carbamoylamino]-3,3-dimethylbutanoyl]-N-[(3S)-1-(cyclopropylamino)-2-hydroxy-1-oxoheptan-3-yl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide
  • Narlaprevir

Related Compounds

  • 6-Cyclopropyl-2-{[1-(3,4-dimethylbenzoyl)azetidin-3-yl]methyl}-2,3-dihydropyridazin-3-one
  • 6-Cyclopropyl-2-{[1-(3,5-dimethylbenzoyl)azetidin-3-yl]methyl}-2,3-dihydropyridazin-3-one
  • 4-(3,5-Dioxomorpholin-4-yl)-N-(2-methylphenyl)piperidine-1-carboxamide
  • 1-[2-(ethylsulfanyl)benzoyl]-4-(1-methyl-1H-imidazol-5-yl)piperidine
  • 2-(2-fluorophenoxy)-1-[4-(1-methyl-1H-imidazol-5-yl)piperidin-1-yl]propan-1-one
  • 6,6-Difluoro-2-azabicyclo[2.2.2]octane
  • 1-(3-Chlorophenyl)-3-[8-(oxan-4-yl)-8-azabicyclo[3.2.1]octan-3-yl]urea
  • 1-(3-Fluoro-8-azabicyclo[3.2.1]octan-8-yl)-3-(4-fluoro-3-methylphenyl)propan-1-one
  • 4-ethyl-N-[2-hydroxy-4-(methylsulfanyl)butyl]-2,3-dioxopiperazine-1-carboxamide
  • 6-Cyclopropyl-2-{[1-(3-methylbenzoyl)azetidin-3-yl]methyl}-2,3-dihydropyridazin-3-one