XE 991 dihydrochloride

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Names

[ CAS No. ]:
122955-42-4

[ Name ]:
XE 991 dihydrochloride

[Synonym ]:
10,10-bis(pyridin-4-ylmethyl)anthracen-9-one,dihydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
625.3ºC at 760mmHg

[ Molecular Formula ]:
C26H20N2O

[ Molecular Weight ]:
376.45

[ Flash Point ]:
332ºC

[ Exact Mass ]:
376.15800

[ PSA ]:
42.85000

[ LogP ]:
4.79250

[ Vapour Pressure ]:
6.84E-16mmHg at 25°C

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
CB1530000

Articles

Loss of Local Astrocyte Support Disrupts Action Potential Propagation and Glutamate Release Synchrony from Unmyelinated Hippocampal Axon Terminals In Vitro.

J. Neurosci. 35 , 11105-17, (2015)

Neuron-astrocyte interactions are critical for proper CNS development and function. Astrocytes secrete factors that are pivotal for synaptic development and function, neuronal metabolism, and neuronal...

Inhibition of post-synaptic Kv7/KCNQ/M channels facilitates long-term potentiation in the hippocampus.

PLoS ONE 7 , e30402, (2012)

Activation of muscarinic acetylcholine receptors (mAChR) facilitates the induction of synaptic plasticity and enhances cognitive function. In the hippocampus, M(1) mAChR on CA1 pyramidal cells inhibit...

Raised activity of L-type calcium channels renders neurons prone to form paroxysmal depolarization shifts.

Neuromolecular Med. 15 , 476-92, (2013)

Neuronal L-type voltage-gated calcium channels (LTCCs) are involved in several physiological functions, but increased activity of LTCCs has been linked to pathology. Due to the coupling of LTCC-mediat...


More Articles

Related Compounds

  • XE 991 dihydrochloride
  • XE 991 dihydrochloride
  • 1-Benzylpiperazine dihydrochloride
  • DIAMIDINO YELLOW DIHYDROCHLORIDE
  • 2-Bromobenzylhydrazine dihydrochloride
  • diethyl diiminoadipate dihydrochloride
  • 3-[(4-chlorophenyl)thio]-5-cyano-2-methyl-1H-indole-1-acetic acid ethyl ester
  • N-(3-(naphthalen-1-yl)-3,4-dihydro-2H-benzo[e][1,3]oxazin-6-yl)acrylamide
  • Tert-butyl 4-(3,4-dichlorobenzyl)-4-(ethoxymethyl)piperidine-1-carboxylate
  • ethyl 3-(6-(tetrahydro-2H-pyran-4-yloxy)imidazo[1,2-b]pyridazin-3-yl)benzoate
  • 3-(1-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)phenol
  • 4-(1-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-ylamino)phenol
  • 7-(Furan-2-yl)-2-(piperazin-1-yl)imidazo[1,2-a][1,3,5]triazin-4-ylamine
  • 6-(2-fluoro-4-trifluoromethyl-phenyl)-N4-(6-methoxy-pyridin-3-yl)-pyrimidine-4,5-diamine
  • 1-[5-[5-[(3-quinolinylamino)methyl]-2-pyridinyl]-2-thienyl]Ethanone
  • 4-(5-{2,5,6-Trifluoro-pyridin-3-yl}-[1,3,4]oxadiazole-2-yl)benzonitrile
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