etynodiol

Suppliers

Names

[ CAS No. ]:
1231-93-2

[ Name ]:
etynodiol

[Synonym ]:
Etinodiol
Ethinodiol
Etinodiol [INN-Spanish]
Etinodiolo [DCIT]
Etynodiol
(3S,8R,9S,10R,13S,14S,17R)-17-ethynyl-13-methyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
Etynodiolum
Etynodiolum [INN-Latin]
Etynodiol [INN:BAN]

Chemical & Physical Properties

[ Density]:
1.15g/cm3

[ Boiling Point ]:
444ºC at 760mmHg

[ Molecular Formula ]:
C20H28O2

[ Molecular Weight ]:
300.43500

[ Flash Point ]:
201.9ºC

[ Exact Mass ]:
300.20900

[ PSA ]:
40.46000

[ LogP ]:
3.28430

[ Vapour Pressure ]:
9.46E-10mmHg at 25°C

[ Index of Refraction ]:
1.585

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RC8961500
CHEMICAL NAME :
19-Nor-17-alpha-pregn-4-en-20-yne-3-beta,17-diol
CAS REGISTRY NUMBER :
1231-93-2
LAST UPDATED :
199512
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C20-H28-O2
MOLECULAR WEIGHT :
300.48
WISWESSER LINE NOTATION :
L E5 B666 MUTJ E1 FQ F1UU1 OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
DOSE :
12 mg/kg
SEX/DURATION :
female 6-20 week(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - behavioral
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 211,1171,1981
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
100 mg/kg
SEX/DURATION :
female 17-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
ECJPAE Endocrinologia Japonica. (Japan Pub. Trading Co., Ltd., POB 5030, Tokyo International, Tokyo, Japan) V.1- 1954- Volume(issue)/page/year: 24,77,1977
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
200 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,57,1965

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Norethindrone
  • Bolandione

DownStream

Related Compounds

  • Etynodiol di(acetate)
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • [(1-ethyl-5-fluoro-3-methyl-1H-pyrazol-4-yl)methyl][(4-fluorophenyl)methyl]amine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 4-(2-Chlorobenzenesulfonyl)-1-(pyridin-3-yl)piperazin-2-one
  • tert-Butyl-DL-alanine