Abemaciclib

Suppliers

Names

[ CAS No. ]:
1231929-97-7

[ Name ]:
Abemaciclib

[Synonym ]:
Abemaciclib
2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-
UNII-60UAB198HK
2-Pyrimidinamine,N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]
N-{5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl}-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzimidazol-6-yl)-2-pyrimidinamine
LY2835219
[5-(4-ethyl-piperazin-1-ylmethyl)-pyridin-2-yl]-[5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-3H-benzoimidazol-5-yl)-pyrimidin-2-yl]-amine
CS-1230
N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
689.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C27H32F2N8

[ Molecular Weight ]:
506.593

[ Flash Point ]:
370.7±34.3 °C

[ Exact Mass ]:
506.271790

[ PSA ]:
75.00000

[ LogP ]:
2.74

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.656

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinamine

DownStream

Related Compounds

  • Abemaciclib mesylate
  • Abemaciclib Metabolites M2
  • 1-(2-Bromo-5-methoxyphenyl)-2,2-difluorocyclopropan-1-amine
  • 4-nitro-3-[(2S)-oxiran-2-yl]-1H-pyrazole
  • 2-(3-(Benzyloxy)-2-methylprop-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 3-(Difluoromethyl)-2,2-dimethylcyclopropan-1-amine
  • 2,2-difluoro-1-(1H-indol-7-yl)ethan-1-one
  • 1,1-Difluoro-2-methyl-3-(4-methyl-1,3-thiazol-5-yl)propan-2-amine
  • 3-(1-ethyl-2,3-dihydro-1H-indol-5-yl)-1,1-difluoro-2-methylpropan-2-amine
  • Methyl 3-(5-bromopyridin-3-yl)-2-hydroxy-3-methylbutanoate
  • Tert-butyl 6-bromo-3-hydroxy-1,2,3,4-tetrahydroquinoline-1-carboxylate
  • tert-butyl N-[3-(2-hydroxy-5-methylphenyl)-3-phenylpropyl]-N-(propan-2-yl)carbamate
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