2-Hydroxy-N-(4-oxo-3(4H)-quinazolinyl)benzamide

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Names

[ CAS No. ]:
123199-81-5

[ Name ]:
2-Hydroxy-N-(4-oxo-3(4H)-quinazolinyl)benzamide

Chemical & Physical Properties

[ Density]:
1.4g/cm3

[ Molecular Formula ]:
C₁₅H₁₁N₃O₃

[ Molecular Weight ]:
281.26600

[ Exact Mass ]:
281.08000

[ PSA ]:
87.71000

[ LogP ]:
1.87000

[ Index of Refraction ]:
1.689

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CV5382500

CHEMICAL NAME :: Benzamide, 2-hydroxy-N-(4-oxo-3(4H)-quinazolinyl)-

CAS REGISTRY NUMBER :: 123199-81-5

LAST UPDATED :: 199103

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C15-H11-N3-O3

MOLECULAR WEIGHT :: 281.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 44,465,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 44,465,1989

Related Compounds

2-(4-Oxo-3(4H)-quinazolinyl)ethyl 2,4-dichlorobenzoate
2-(4-Oxo-3(4H)-quinazolinyl)butanoic acid
2-(4-Oxo-3(4H)-quinazolinyl)ethyl 5-bromo-2-furoate
O-amino-N-[2-mercapto-4-oxo-3-(4H)-quinazolinyl]-benzamide
-bta--Alanine,N-(3-ethoxy-3-oxopropyl)-N-[2-hydroxy-3-(6,7,8-trimethoxy-2-methyl-4-oxo-3(4H)-quinazolinyl)propyl]-,ethyl ester
Propanenitrile,3-[[2-hydroxy-3-(6,7,8-trimethoxy-2-methyl-4-oxo-3(4H)-quinazolinyl)propyl]methylamino]-