Bicyclo[2.2.1]hept-5-ene-2-acetic acid, 2,5-dioxo-1-pyrrolidinyl ester

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Names

[ Name ]:
Bicyclo[2.2.1]hept-5-ene-2-acetic acid, 2,5-dioxo-1-pyrrolidinyl ester

[Synonym ]:
2,5-Pyrrolidinedione, 1-[(2-bicyclo[2.2.1]hept-5-en-2-ylacetyl)oxy]-
1-[2-(Bicyclo[2.2.1]hept-5-en-2-yl)acetoxy]-2,5-pyrrolidinedione

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
369.8±25.0 °C at 760 mmHg

[ Melting Point ]:
115-120°C

[ Molecular Formula ]:
C₁₃H₁₅NO₄

[ Molecular Weight ]:
249.262

[ Flash Point ]:
177.4±23.2 °C

[ Exact Mass ]:
249.100113

[ LogP ]:
0.25

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.580

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

Articles

Tetrazine-based cycloadditions: application to pretargeted live cell imaging.

Bioconjug. Chem. 19 , 2297-2299, (2008)

Bioorthogonal tetrazine cycloadditions have been applied to live cell labeling. Tetrazines react irreversibly with the strained dienophile norbornene forming dihydropyrazine products and dinitrogen. T...

Development of a bioorthogonal and highly efficient conjugation method for quantum dots using tetrazine-norbornene cycloaddition.

J. Am. Chem. Soc. 132 , 7838-7839, (2010)

We present a bioorthogonal and modular conjugation method for efficient coupling of organic dyes and biomolecules to quantum dots (QDs) using a norbornene-tetrazine cycloaddition. The use of noncoordi...