XMD8-92

Suppliers

Names

[ Name ]:
XMD8-92

[Synonym ]:
2-{[2-Ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 2-[[2-ethoxy-4-(4-hydroxy-1-piperidinyl)phenyl]amino]-5,11-dihydro-5,11-dimethyl-
XMD8-92
2-(2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
741.8±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₆H₃₀N₆O₃

[ Molecular Weight ]:
474.555

[ Flash Point ]:
402.4±35.7 °C

[ Exact Mass ]:
474.237946

[ PSA ]:
97.44000

[ LogP ]:
1.14

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.655

[ Storage condition ]:
-20℃

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Dual role of ERK5 in the regulation of T cell receptor expression at the T cell surface.

J. Leukoc. Biol. 99 , 143-52, (2016)

Regulation of the levels of the TCR/CD3 complex at the cell surface is critical to proper T cell development and mature T cell activation. We provide evidence that the MAPK ERK5 regulates the surface ...