Zatosetron (maleate)

Suppliers

Names

[ CAS No. ]:
123482-23-5

[ Name ]:
Zatosetron (maleate)

[Synonym ]:
Zatosetron (maleate)

Chemical & Physical Properties

[ Boiling Point ]:
435.1ºC at 760 mmHg

[ Molecular Formula ]:
C23H29ClN2O6

[ Molecular Weight ]:
464.94

[ Flash Point ]:
216.9ºC

[ PSA ]:
45.06000

[ LogP ]:
3.92120

[ Vapour Pressure ]:
8.99E-08mmHg at 25°C

[ Storage condition ]:
2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DF6473550
CAS REGISTRY NUMBER :
123482-23-5
LAST UPDATED :
199510
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H25-Cl-N2-O2.C4-H4-O4
MOLECULAR WEIGHT :
464.99

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
38220 mg/kg/1Y-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
REFERENCE :
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 22,494,1994
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
3650 mg/kg/1Y-I
TOXIC EFFECTS :
Cardiac - EKG changes not diagnostic of specified effects
REFERENCE :
DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 18,61,1995

Related Compounds

  • TPN729 maleate
  • lead maleate
  • Dioctyl maleate
  • Dibutyltin Maleate Polymer n=2-3
  • METHOXYPROMAZINE MALEATE
  • (Z)-but-2-enedioic acid,(1S,5R)-3-(6,11-dihydro-5H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yloxy)-8-methyl-8-azabicyclo[3.2.1]octane
  • Isoquinoline,1,2,3,4-tetrahydro-2-(2-methoxyphenyl)-
  • 4-Oxo-4-(((2R,3R,4S,5R,6R)-3,4,5-triacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)amino)butanoic acid
  • 1-(2-Fluorophenyl)-1,5,6,7-tetrahydro-4H-indazol-4-one
  • N-(4-{[2-(5-bromo-2-methoxyphenyl)-1,3-thiazol-4-yl]methylthio}phenyl)acetamid e
  • 2-[(5-benzyl-4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-1-(2,4,6-trimethylphenyl)ethan-1-one
  • N1-(2-chlorobenzyl)-N2-(2-(furan-2-yl)-2-(phenylsulfonyl)ethyl)oxalamide
  • methyl 2-(2-{[4-amino-5-(3-chlorophenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamido)acetate
  • 4,8-dimethyl-7-{[5-(pyrrolidine-1-sulfonyl)pyridin-2-yl]oxy}-2H-chromen-2-one
  • 2-chloro-N-(2-(furan-2-yl)-2-(indolin-1-yl)ethyl)-4-nitrobenzamide
  • N-benzyl-2-({6-oxo-5-[(thiophen-2-yl)methyl]-8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,10,12-pentaen-4-yl}sulfanyl)acetamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.