(2R,3S,5R)-2-((((2,3-dimethylbutan-2-yl)dimethylsilyl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl methanesulfonate

Names

[ CAS No. ]:
123533-04-0

[ Name ]:
(2R,3S,5R)-2-((((2,3-dimethylbutan-2-yl)dimethylsilyl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl methanesulfonate

Chemical & Physical Properties

[ Molecular Formula ]:
C19H34N2O7SSi

[ Molecular Weight ]:
462.63300

[ Exact Mass ]:
462.18600

[ PSA ]:
125.07000

[ LogP ]:
3.21600

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 5'-O-[dimethyl(1,1,2-trimethylpropyl)silyl]thymidine
  • Methanesulfonyl chloride

DownStream

  • 3'-Amino-3'-deoxythymidine
  • Zidovudine
  • N-[(2S,3S,5R)-2-(hydroxymethyl)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]formamide

Related Compounds

  • 2-[N-ethyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2,2-difluoropropanamido]acetic acid
  • 5-chloro-2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]benzoic acid
  • Benzyl 3-bromo-2-formyl-6,7-dihydropyrazolo[1,5-a]pyrazine-5(4H)-carboxylate
  • 4-(4,4-Difluorocyclohexyl)butanal
  • 5-Amino-3-bromo-1-(2-cyclobutylethyl)-1,2-dihydropyridin-2-one
  • 4-(3-Chloro-4-ethoxyphenyl)morpholin-3-one
  • 5-(3-Oxomorpholin-4-yl)benzene-1,3-dicarboxylic acid
  • 5-(1,1-difluoropropyl)-4-propyl-4H-1,2,4-triazole-3-thiol
  • 3-[(3-Methoxycyclohexyl)oxy]-2,3-dihydro-1lambda6-thiophene-1,1-dione
  • 9-Methyl-2-propyl-1-oxa-5,9-diazaspiro[5.6]dodecane
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