(3S,6R,7S,8S,12Z,15S,16E)-15-(tert-butyldimethylsiloxy)-3,7-dihydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methylthiazol-4-yl)-5-oxaheptadeca-12,16-dienic acid

Names

[ CAS No. ]:
1236206-72-6

[ Name ]:
(3S,6R,7S,8S,12Z,15S,16E)-15-(tert-butyldimethylsiloxy)-3,7-dihydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methylthiazol-4-yl)-5-oxaheptadeca-12,16-dienic acid

Chemical & Physical Properties

[ Molecular Formula ]:
C33H57NO6SSi

[ Molecular Weight ]:
623.95900

[ Exact Mass ]:
623.36800

[ PSA ]:
145.19000

[ LogP ]:
7.81590

Synthetic Route

Precursor & DownStream

Precursor

  • 2-{(7S)-5,5-dimethyl-4,6-dioxaspiro[2.5]oct-7-yl}-2-methylpentan-3-one

DownStream

  • Epothilone D
  • (3S,7S,8S,12Z,15S,16E)-3,7,15-tris[[tert-butyl(dimethyl)silyl]oxy]-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)-5-oxoheptadeca-12,16-dienoic acid

Related Compounds

  • (2E)-2-(4-Chlorobenzylidene)-5,5-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentane-1,3-diol
  • 3-[N-ethyl-S-[methyl(propyl)amino]sulfonimidoyl]aniline
  • (1alpha,2beta,10beta)-2,7-Dihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid
  • (4S,5R,6S)-3-((1,1-Dioxido-6-(2-(4-propyl-1,4-diazoniabicyclo[2.2.2]octan-1-yl)ethyl)-2H-naphtho[1,8-cd][1,2]thiazol-2-yl)methyl)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
  • 1-Phenyl-1H-benzotriazole-5-sulfonamide
  • 1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen1-yl]-5-methyl-5-(1-methylpropyl)-, cis-
  • [2-(Aminomethyl)-1-(3-fluorophenyl)cyclopropyl]methanol
  • 1,3-Dioxane, 2-[(1S,2R)-2,4-dimethyl-3-cyclohexen1-yl]-5-methyl-5-(1-methylpropyl)-, cis-
  • 3-(3-Carbamoyl-5-((5-((4-chloro-6-(4-(ethenylsulfonyl)anilino)-1,3,5-triazin-2-yl)amino)-2-sulfophenyl)diazenyl)-6-hydroxy-4-methyl-2-oxopyridin-1(2H)-yl)propanoic acid
  • 4-[(3-Hydroxyphenyl)sulfonyl]-2-thiophenesulfonamide
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