(11S,12R)-EET

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Names

[ CAS No. ]:
123931-40-8

[ Name ]:
(11S,12R)-EET

[Synonym ]:
5,8-Decadienoic acid, 10-[(2S,3R)-3-[(2Z)-2-octen-1-yl]oxiranyl]-, (5Z,8Z)-
(5Z,8Z)-10-{(2S,3R)-3-[(2Z)-2-Octen-1-yl]-2-oxiranyl}-5,8-decadienoic acid
(11S,12R)-EET
(5Z,8Z)-10-{(2S,3R)-3-[(2Z)-oct-2-en-1-yl]oxiran-2-yl}deca-5,8-dienoic acid
(5Z,8Z)-10-{(2S,3R)-3-[(2Z)-2-Octen-1-yl]-2-oxiranyl}-5,8-decadie noic acid

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
461.8±33.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H32O3

[ Molecular Weight ]:
320.466

[ Flash Point ]:
154.6±18.9 °C

[ Exact Mass ]:
320.235138

[ PSA ]:
49.83000

[ LogP ]:
6.30

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.501

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H319

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235

[ RIDADR ]:
UN1170 - class 3 - PG 2 - Ethanol, solution

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 7-carbomethoxy hepta-3-(Z)-en-1-ylidenetriphenylphosphorane
  • Phosphorane of (Z)-3-nonen-1-yl-triphenylphosponium bromide
  • Arachidonic acid

DownStream

Articles

Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor.

Br. J. Pharmacol. 172(3) , 910-23, (2015)

Long-term intake of dietary fatty acids is known to predispose to chronic inflammation, but their effects on acute intestinal ischaemia/reperfusion (I/R) injury is unknown. The aim of this study was t...

Cyp2c44 epoxygenase in the collecting duct is essential for the high K+ intake-induced antihypertensive effect.

Am. J. Physiol. Renal Physiol. 307(4) , F453-60, (2014)

Cytochrome P-450, family 2, subfamily c, polypeptide 44 (Cyp2c44) epoxygenase metabolizes arachidonic acid (AA) to epoxyeicosatrienoic acids (EETs) in kidney and vascular tissues. In the present study...

UHPLC-MS/MS analysis of arachidonic acid and 10 of its major cytochrome P450 metabolites as free acids in rat livers: effects of hepatic ischemia.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 964 , 153-63, (2014)

The cytochrome P450 metabolites of arachidonic acid (AA) are mostly present in tissues, such as the liver, as bound to phospholipids, with only a small fraction available as free acids. The purpose of...


More Articles

Related Compounds

  • (11S,12R,13R)-(9Z,15Z)-11,12,13-Trihydroxyoctadeca-9,15-dienoic acid
  • (11S,12R,13R,14S)-11,12-dihydroxy-13,14-epoxy-11,12,13,14-tetrahydrobenzochrysene
  • (11S,12R)-3-methyl-1,2,11,12-tetrahydrobenzo[j]aceanthrylene-11,12-diol
  • (9S,10R,11S,12R)-9,10,11,12-Tetrahydro-benzo[e]pyrene-9,10,11,12-tetraol
  • (3E,7E,11S,12R)-4,8,12,15,15-pentamethylbicyclo[9.3.1]pentadeca-3,7-dien-12-ol
  • [(4R,5S,11S,12R)-5,11,12-triacetyloxy-4,5,11,12-tetrahydrobenzo[a]pyren-4-yl] acetate