2-(2-Butoxyethoxy)ethyl acetate

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Names

[ CAS No. ]:
124-17-4

[ Name ]:
2-(2-Butoxyethoxy)ethyl acetate

[Synonym ]:
ETHANOL,2-(2-BUTOXYETHOXY)-, 1-ACETATE
DIETHYLENEGLYCOLMONOBUTYLETHERACETATE
DIETHYLENEGLYCOL MONOBUTYL ETHER ACETATE
Butyldiglycol acetate,DB Acetate,Diethylene glycol monobutyl ether acetate
GLYCOL ETHER DB ACETATE: CP
DIETHYLENE GLYCOL BUTYL ETHER ACETATE
BUTYLDIGLYCOL ACETATE
Butyl Carbitol Acetate
DIETHYLENE GLYCOL MONO-BUTYL ETHER ACETATE
2-(2-Butoxyethoxy)ethyl Acetate
Diethylene glycol monobutyl ether acetate
MFCD00009458
2-(2-N-BUTOXYETHOXY)ETHYL ACETATE/BUTYLDIGLYCOL ACETATE/DIETHYLENE GLYCOL MONO-N-BUTYL ETHER ACETATE
Diethyl.glycol-mbutylether acetate
Diethylene Glycol Butylether Acetate
2-(2-N-BUTOXYETHOXY)ETHYL ACETATE
DIETHYLENE GLYCOL MONOBUTHYL ETHER ACETATE(DBAC)
EINECS 204-685-9
DIETHYLENEGLYCOL MONOBUTYLETHERACETATE
2-(2-BUTOXYETHOXY)ETHYL] ACETATE FOR SYNTHESIS
2-(2-BUTOXYETHOXY) ETHYL ACETATE (1 LT GLS)
DIETHYLENE GLYCOL MONOBUTHYL ETHER ACETATE (DBAC)
DIETHYLENE GLYCOL MONOBUTYL ETHER ACETATE (DBAC)
DIETHYLENE GLYCOL MONO-N-BUTYL ETHER ACETATE
[2-(2-BUTOXYETHOXY)ETHYL] ACETATE

Chemical & Physical Properties

[ Density]:
0.977 g/mL at 20 °C(lit.)

[ Boiling Point ]:
245 °C(lit.)

[ Melting Point ]:
-32 °C

[ Molecular Formula ]:
C10H20O4

[ Molecular Weight ]:
204.26300

[ Flash Point ]:
105 °C

[ Exact Mass ]:
204.13600

[ PSA ]:
44.76000

[ LogP ]:
1.38280

[ Vapour Pressure ]:
8.03E-06mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.426

[ Stability ]:
Stable, but may be light sensitive. Combustible. Incompatible with strong oxidizing agents, acids, strong bases.

[ Water Solubility ]:
65 g/L

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KJ9275000
CHEMICAL NAME :
Ethanol, 2-(2-butoxyethoxy)-, acetate
CAS REGISTRY NUMBER :
124-17-4
BEILSTEIN REFERENCE NO. :
1771533
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C10-H20-O4
MOLECULAR WEIGHT :
204.30
WISWESSER LINE NOTATION :
4O2O2OV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 12/29/1971
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969 Volume(issue)/page/year: 5,32,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6600 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2260 mg/kg
TOXIC EFFECTS :
Behavioral - sleep
REFERENCE :
38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985. Volume(issue)/page/year: 2C,4028,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
14500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,27,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
2340 mg/kg
TOXIC EFFECTS :
Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
5 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
180 mL/kg/13W-I
TOXIC EFFECTS :
Behavioral - muscle weakness Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 93,26,1948 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83639 No. of Facilities: 1483 (estimated) No. of Industries: 35 No. of Occupations: 38 No. of Employees: 21417 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83639 No. of Facilities: 3243 (estimated) No. of Industries: 42 No. of Occupations: 46 No. of Employees: 45220 (estimated) No. of Female Employees: 10562 (estimated)

Safety Information

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R19;R36/37

[ Safety Phrases ]:
S39-S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
KJ9275000

[ HS Code ]:
2942000000

Synthetic Route

Precursor & DownStream

Precursor

  • 2-(2-Butoxyethoxy)ethanol
  • acetic acid
  • Ethanoic anhydride

DownStream

Customs

[ HS Code ]: 2915390090

[ Summary ]:
2915390090. esters of acetic acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:5.5%. General tariff:30.0%

Articles

Delayed and immediate hypersensitivity to carbitols.

Contact Dermatitis 21(1) , 52-3, (1989)

Biomonitoring of 2-(2-alkoxyethoxy)ethanols by analysing urinary 2-(2-alkoxyethoxy)acetic acids.

Toxicol. Lett. 156(1) , 117-26, (2005)

2-Methoxyacetic and 2-ethoxyacetic acids are well known toxic metabolites of 2-alkoxyethanols. The use of 2-alkoxyethanols is now restricted, and the regulations have forced manufacturers to find subs...

Metabolic studies with diethylene glycol monobutyl ether acetate (DGBA) in the rat.

Xenobiotica 19(9) , 981-9, (1989)

1. The in vitro hydrolysis of DGBA in rat blood and its in vivo metabolism and disposition in male Sprague-Dawley rats were studied. 2. DGBA (5 mM) was hydrolysed in rat blood to diethylene glycol mon...


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Related Compounds

  • 2-(2-Butoxyethoxy)ethyl acetate
  • 2-(2-butoxyethoxy)ethyl dihydrogen phosphate,N,N-dimethylcyclohexanamine
  • 2-(2-butoxyethoxy)ethyl 2-cyanoacetate
  • 2-(2-butoxyethoxy)ethyl 2-chloroacetate
  • 2-(2-butoxyethoxy)ethyl thiocyanate,thiocyanatomethyl dodecanoate
  • 2-(2-butoxyethoxy)ethyl octanoate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 1-(2,4-difluorophenyl)-1H,4H,5H,6H-cyclopenta[c]pyrazole-3-carboxylic acid
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 3-Fluoro-2-methyl-6-nitrobenzotrifluoride
  • Cyclopropanecarboxylic acid, 2,2-difluoro-3-[[(4-methoxyphenyl)methoxy]methyl]-, ethyl ester, (1R,3R)-rel-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde