Dodecanamine

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Names

[ CAS No. ]:
124-22-1

[ Name ]:
Dodecanamine

[Synonym ]:
Dibenzo[b,e][1,4]dioxin-1-amine
Laurylamine
1-dodecanamine
1-lauryl amine
dodecyl amine
1-dodecylamine
1-Aminodibenzo-p-dioxin
1-Aminododecane,Laurylamine
EINECS 204-690-6
MFCD00008154
1-aminododecane
Dibenzo[b,4]-dioxin-1-amine
DodecylaMine

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
247-249 ºC

[ Melting Point ]:
28-32 ºC

[ Molecular Formula ]:
C12H27N

[ Molecular Weight ]:
185.350

[ Flash Point ]:
100.4±13.1 °C

[ Exact Mass ]:
185.214355

[ PSA ]:
26.02000

[ LogP ]:
5.18

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.444

[ Stability ]:
Stable. Combustible. Incompatible with acid chlorides, acids, acid anhydrides, oxidizing agents.

[ Water Solubility ]:
78 mg/L (25 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JR6475000
CHEMICAL NAME :
Dodecylamine
CAS REGISTRY NUMBER :
124-22-1
BEILSTEIN REFERENCE NO. :
1633576
LAST UPDATED :
199710
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C12-H27-N
MOLECULAR WEIGHT :
185.40
WISWESSER LINE NOTATION :
Z12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,438,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,438,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 219,119,1953 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1020 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 219,119,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1160 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 219,119,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1342 No. of Facilities: 47 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 377 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1342 No. of Facilities: 21 (estimated) No. of Industries: 2 No. of Occupations: 15 No. of Employees: 2134 (estimated) No. of Female Employees: 306 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H304-H314-H335-H373-H410

[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P305 + P351 + P338-P310

[ Target Organs ]:
Gastrointestinal tract, Immune system, Liver

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R20/21/22;R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S60-S61

[ RIDADR ]:
UN 3259 8/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
JR6475000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2921199090

Synthetic Route

Precursor & DownStream

Precursor

  • N-trityldodecan-1-amine
  • Lauric nitrile
  • 1-azidododecane
  • 1-Dodecanol
  • Lauramide
  • Lauric acid
  • Methyl laurate

DownStream

  • Benzamide,N-dodecyl-2-hydroxy-
  • Propanamide,3,3'-thiobis[N-dodecyl-
  • Propanenitrile,3-(dodecylamino)-
  • 3, 3'-(Dodecylazanediyl)dipropanenitrile
  • 1-Dodecylimidazole
  • Domiphen bromide
  • dodecan-1-amine; dodecanoic acid
  • prop-2-ynyl N-dodecylcarbamate
  • 1-Isocyanatododecane
  • dodecylamine hydrochloride

Customs

[ HS Code ]: 2921199090

[ Summary ]:
2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • 1-dodecanamine
  • 1-Dodecanamine
  • 2-Dodecanamine
  • tert-Dodecanamine
  • 1-Dodecanamine,2-octyl
  • 1-Dodecanamine,nitrate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • N-ethyl-1-(oxane-4-carbonyl)pyrrolidin-3-amine
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 4-ethyl-3-methyl-N-propylbenzene-1-sulfonamide
  • tert-Butyl-DL-alanine