1,1-dimethylethyl [methyl-6-hydroximino-5,6,7,8,9-pentadeoxy-9(S)-[[(4-methylphenyl)sulfonyl]amino]-2,3-O-(1-methylethylidene)-β-D-ribo-dec-5-enofuranosid]uronates

Names

[ CAS No. ]:
124288-78-4

[ Name ]:
1,1-dimethylethyl [methyl-6-hydroximino-5,6,7,8,9-pentadeoxy-9(S)-[[(4-methylphenyl)sulfonyl]amino]-2,3-O-(1-methylethylidene)-β-D-ribo-dec-5-enofuranosid]uronates

Chemical & Physical Properties

[ Molecular Formula ]:
C25H38N2O9S

[ Molecular Weight ]:
542.64200

[ Exact Mass ]:
542.23000

[ PSA ]:
150.36000

[ LogP ]:
4.34720

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,1-dimethylethyl [methyl-6-nitro-5,6,7,8,9,-pentadeoxy-9(S)-[[(4-methylphenyl)sulfonyl]amino]-2,3-O-(1-methyl-ethylidene)-β-D-ribo-dec-5-enofuranosid]uronates
  • (2S,6R)-tert-butyl 6-hydroxy-6-((3aR,4R,6R,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-2-(4-methylphenylsulfonamido)-5-nitrohexanoate

DownStream

  • Sinefungin
  • (2S,5S)-5-amino-6-((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-(4-methylphenylsulfonamido)hexanoic acid compound with 2,2,2-trifluoroacetic acid (1:1)