Mefeclorazine
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Names
[ CAS No. ]:
1243-33-0
[ Name ]:
Mefeclorazine
[Synonym ]:
1-(2-chloro-phenyl)-4-(3,4-dimethoxy-phenethyl)-piperazine
Mefeclorazina [INN-Spanish]
4-<2-Chlor-phenyl>-1-<3,4-dimethoxy-phenethyl>-piperazin
1-o-Chlorophenyl-4-(3,4-dimethoxyphenethyl)piperazine
Mefeclorazinum [INN-Latin]
1-(2-Chlorphenyl)-4-(3,4-dimethoxyphenethyl)piperazine
N-(Dimethoxy-3,4-phenethyl),-N'-(chloro-2-phenyl) piperazine
Piperazine,1-(o-chlorophenyl)-4-(3,4-dimethoxyphenethyl)
Mefeclorazine
SD 218-06
Mepheclorazin
Chemical & Physical Properties
[ Density]:
1.16g/cm3
[ Boiling Point ]:
490.1ºC at 760 mmHg
[ Molecular Formula ]:
C20H25ClN2O2
[ Molecular Weight ]:
360.87800
[ Flash Point ]:
250.2ºC
[ Exact Mass ]:
360.16000
[ PSA ]:
24.94000
[ LogP ]:
3.72480
[ Vapour Pressure ]:
9.43E-10mmHg at 25°C
[ Index of Refraction ]:
1.57
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TL2803000
- CHEMICAL NAME :
- Piperazine, 1-(o-chlorophenyl)-4-(3,4-dimethoxyphenethyl)-
- CAS REGISTRY NUMBER :
- 1243-33-0
- BEILSTEIN REFERENCE NO. :
- 0627902
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C20-H25-Cl-N2-O2
- MOLECULAR WEIGHT :
- 360.92
- WISWESSER LINE NOTATION :
- T6N DNTJ A2R CO1 DO1& DR CG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSCBAY Psychopharmacology Service Center, Bulletin. (Bethesda, MD) V.1-3, 1961-65. For publisher information, see PSYBB9. Volume(issue)/page/year: 2,17,1963
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - central sympatholytic Vascular - BP elevation not characterized in autonomic section Lungs, Thorax, or Respiration - bronchiolar dilation
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,104,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 55 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 133,29,1961
Safety Information
[ HS Code ]:
2933599090
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%