[(2R,3R,4R,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-4-methylsulfonyloxy-2-(trityloxymethyl)oxolan-3-yl] methanesulfonate

Names

[ CAS No. ]:
124493-84-1

[ Name ]:
[(2R,3R,4R,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-4-methylsulfonyloxy-2-(trityloxymethyl)oxolan-3-yl] methanesulfonate

[Synonym ]:
Uridine,5-methyl-5'-O-(triphenylmethyl)-,2',3'-dimethanesulfonate
5-Methyl-5'-O-(triphenylmethyl)uridine 2',3'-dimethansulfonate
Dimesyl-trityl-T
5-methyl-5'-O-(triphenylmethyl)uridine 2',3'-bis(methanesulfonate)

Chemical & Physical Properties

[ Density]:
1.46g/cm3

[ Molecular Formula ]:
C31H32N2O10S2

[ Molecular Weight ]:
656.72300

[ Exact Mass ]:
656.15000

[ PSA ]:
177.08000

[ LogP ]:
5.01460

[ Index of Refraction ]:
1.654

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanesulfonyl chloride
  • Triphenylmethyl Chloride
  • 5-Methyluridine

DownStream

  • 5'-o-trityl-2',3'-dehydrothymidine
  • 1-[(2R,3S,4S,5S)-4-azido-3-hydroxy-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 1-[(2R,3S,4S,5R)-3-azido-4-fluoro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 1-[(2R,3S,4S,5R)-3-azido-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 1-[(2R,3R,4R,5S)-4-azido-3-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 1-[(2R,3R,4R,5S)-4-azido-3-fluoro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • 5-methyl-1-[(2R,4R)-4-(trityloxymethyl)-3,6-dioxabicyclo[3.1.0]hexan-2-yl]pyrimidine-2,4-dione
  • 1-[(2R,3R,4R,5R)-3-azido-4-hydroxy-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Related Compounds

  • 5,6-Dichloro-2-[(4-methoxyphenyl)methyl]pyridazin-3-one
  • 3-[4-(Dimethylamino)phenyl]-3-fluoro-2,2-dimethylpropanoic acid
  • 3-(3-Ethoxyphenyl)-3-fluoro-2,2-dimethylpropanoic acid
  • 3-(2-Amino-1-fluoro-2-methylpropyl)aniline
  • 4-(2-amino-1-fluoro-2-methylpropyl)-N,N-diethylaniline
  • (2S)-4-(2,3-dihydro-1H-inden-1-yl)butan-2-amine
  • 3-(3-Bromophenyl)-3-fluoro-2,2-dimethylpropan-1-ol
  • 2-(4-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)piperazin-1-yl)acetic acid
  • (R,E)-3-(4-(tert-Butoxycarbonyl)morpholin-2-yl)acrylic acid
  • 3-Fluoro-2,2-dimethyl-3-(2-methylphenyl)propan-1-ol
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