propicillin potassium

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Names

[ Name ]:
propicillin potassium

[Synonym ]:
propicillin,potassium salt
baycillinpotassium
baycillin
EINECS 214-993-5
potassiumpropicillin
PROPICILLIN POTASSIUM
brocillin
Potassium procillin

Chemical & Physical Properties

[ Boiling Point ]:
675.5ºC at 760mmHg

[ Molecular Formula ]:
C₁₈H₂₁KN₂O₅S

[ Molecular Weight ]:
416.53300

[ Flash Point ]:
362.3ºC

[ Exact Mass ]:
416.08100

[ PSA ]:
124.07000

[ LogP ]:
0.46980

[ Vapour Pressure ]:
3.59E-19mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XH9300000

CHEMICAL NAME :: 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6- (2-phenoxybutyramido)-, monopotassium salt

CAS REGISTRY NUMBER :: 1245-44-9

LAST UPDATED :: 199309

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C18-H21-N2-O5-S.K

MOLECULAR WEIGHT :: 416.57

WISWESSER LINE NOTATION :: T45 ANV ESTJ CMVY2&OR& F1 F1 GVQ &-KA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,751,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,751,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 292 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 31,232,1968

Related Compounds

N-benzyl-1-phenylmethanamine,3,3-dimethyl-7-oxo-6-(2-phenoxybutanoylamino)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
propicillin
beryllium,potassium,trifluoride
calcium,potassium,disodium,(2S)-2-hydroxypropanoate,dichloride,dihydroxide,hydrate
zirconium potassium chloride
(Z)-potassium butanediazotate
O-[2-(3-bromo-5-methylthiophen-2-yl)ethyl]hydroxylamine
3-(6-Bromopyridin-3-yl)-3,3-difluoropropan-1-amine
4-Bromo-3-cyclopropyl-1,2-oxazole
4-(Aminomethyl)-4-[5-(trifluoromethyl)thiophen-2-yl]cyclohexan-1-ol
3-(But-3-yn-2-yl)benzene-1,2-diol
5-(2-Methyloxolan-3-yl)-1,2-oxazol-3-amine
7-(4-Chlorophenyl)-8-hydroxy-5-oxaspiro[3.4]oct-7-en-6-one
4-Azaspiro[2.4]heptane-7-carbaldehyde
2-(aminomethyl)-2-ethyl-butanal
3-[(5-Bromothiophen-2-yl)oxy]-3-methylazetidine

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