5-(4-chlorophenyl)-5-hydroxy-2-oxooxolane-3-carbonitrile

Names

[ Name ]:
5-(4-chlorophenyl)-5-hydroxy-2-oxooxolane-3-carbonitrile

[Synonym ]:
Tetrahydro-5-(4-chlorophenyl)-5-hydroxy-2-oxo-3-furancarbonitrile
3-Furancarbonitrile,tetrahydro-5-(4-chlorophenyl)-5-hydroxy-2-oxo
3-Cyano-5-(p-chlorophenyl)-5-hydroxytetrahydrofuran-2-one

Chemical & Physical Properties

[ Density]:
1.48g/cm3

[ Boiling Point ]:
520.3ºC at 760mmHg

[ Molecular Formula ]:
C₁₁H₈ClNO₃

[ Molecular Weight ]:
237.63900

[ Flash Point ]:
268.5ºC

[ Exact Mass ]:
237.01900

[ PSA ]:
70.32000

[ LogP ]:
1.57178

[ Vapour Pressure ]:
1.19E-11mmHg at 25°C

[ Index of Refraction ]:
1.615

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LT9850000

CHEMICAL NAME :: 3-Furancarbonitrile, tetrahydro-5-(4-chlorophenyl)-5-hydroxy-2-oxo-

CAS REGISTRY NUMBER :: 124500-03-4

LAST UPDATED :: 199103

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C11-H8-Cl-N-O3

MOLECULAR WEIGHT :: 237.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1811 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 41,77,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 543 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25- 1973- Volume(issue)/page/year: 41,77,1989

Related Compounds

2-(4-chlorophenoxy)-N-(1-methyl-2-oxo-5-(pyrrolidine-1-carbonyl)-1,2-dihydropyridin-3-yl)acetamide
Methyl 2-(2-(benzo[d][1,3]dioxol-5-yl)acetamido)thiophene-3-carboxylate
2-(2-(Benzo[d][1,3]dioxol-5-yl)acetamido)thiophene-3-carboxamide
2-(2-(benzo[d][1,3]dioxol-5-yl)acetamido)-N-methylthiophene-3-carboxamide
N-(1-methyl-2-oxo-5-(pyrrolidine-1-carbonyl)-1,2-dihydropyridin-3-yl)-2-(naphthalen-2-yloxy)acetamide
2-(2-methoxyphenoxy)-N-[1-methyl-2-oxo-5-(pyrrolidine-1-carbonyl)-1,2-dihydropyridin-3-yl]acetamide
2-(4-ethoxyphenoxy)-N-(1-methyl-2-oxo-5-(pyrrolidine-1-carbonyl)-1,2-dihydropyridin-3-yl)acetamide
2-(benzo[d][1,3]dioxol-5-yl)-N-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)acetamide
2-(benzo[d][1,3]dioxol-5-yl)-N-(5-(2-methoxyphenyl)-1,3,4-oxadiazol-2-yl)acetamide
2-(benzo[d][1,3]dioxol-5-yl)-N-(5-(3-methoxyphenyl)-1,3,4-oxadiazol-2-yl)acetamide

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