AM 6545

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Names

[ CAS No. ]:
1245626-05-4

[ Name ]:
AM 6545

[Synonym ]:
AM-6545
5-(4-(4-cyanobut-1-ynyl)phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxothiomorpholino)-1H-pyrazole-3-carboxamide

Chemical & Physical Properties

[ Molecular Formula ]:
C26H23Cl2N5O3S

[ Molecular Weight ]:
556.46400

[ Exact Mass ]:
555.09000

[ PSA ]:
119.96000

[ LogP ]:
5.77848

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Cyano-1-butyne

DownStream

Articles

Fasting stimulates 2-AG biosynthesis in the small intestine: role of cholinergic pathways.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 309 , R805-13, (2015)

The endocannabinoids are lipid-derived signaling molecules that control feeding and energy balance by activating CB1-type cannabinoid receptors in the brain and peripheral tissues. Previous studies ha...

RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase.

Nat. Commun. 5 , 4657, (2014)

Host immune cells can detect and destruct invading pathogens via pattern-recognition receptors. Small Rap GTPases act as conserved molecular switches coupling extracellular signals to various cellular...


More Articles

Related Compounds

  • AM-5308
  • AM-0466
  • AM-1091
  • AM-1488
  • AM 2394
  • AM-6494
  • Ethyl 1-(piperidin-1-ylmethyl)cyclopropanecarboxylate
  • (R)-1-benzyl-3,3-difluoropiperidin-4-ol
  • (2S,4S)-tert-Butyl 4-amino-2-phenylpyrrolidine-1-carboxylate
  • [3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]methanol
  • 1H-Pyrazole-3-carboxylic acid, 1-(3-chloro-2-pyridinyl)-5-(2-furanyl)-, butyl ester
  • (5-Methoxy-6-(trifluoromethyl)pyridin-2-yl)methanamine
  • 5-Bromo-2-(1H-imidazol-2-yl)-3-methoxypyridine
  • 2,4-Dichloro-5-(1H-imidazol-2-yl)pyridine
  • potassium 2-(1-methyl-1H-imidazol-5-yl)-2-oxoacetate
  • 4-(Benzyloxy)-6-ethynylpyridin-2-ol
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