AM 6545

Names

[ Name ]:
AM 6545

[Synonym ]:
AM-6545
5-(4-(4-cyanobut-1-ynyl)phenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(1,1-dioxothiomorpholino)-1H-pyrazole-3-carboxamide

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₃Cl₂N₅O₃S

[ Molecular Weight ]:
556.46400

[ Exact Mass ]:
555.09000

[ PSA ]:
119.96000

[ LogP ]:
5.77848

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Fasting stimulates 2-AG biosynthesis in the small intestine: role of cholinergic pathways.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 309 , R805-13, (2015)

The endocannabinoids are lipid-derived signaling molecules that control feeding and energy balance by activating CB1-type cannabinoid receptors in the brain and peripheral tissues. Previous studies ha...

RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase.

Nat. Commun. 5 , 4657, (2014)

Host immune cells can detect and destruct invading pathogens via pattern-recognition receptors. Small Rap GTPases act as conserved molecular switches coupling extracellular signals to various cellular...

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