(4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid

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Names

[ CAS No. ]:
1246616-73-8

[ Name ]:
(4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid

[Synonym ]:
Dolutegravir Intermediate2

Chemical & Physical Properties

[ Molecular Formula ]:
C13H14N2O6

[ Molecular Weight ]:
294.26000

[ Exact Mass ]:
294.08500

[ PSA ]:
109.07000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Dimethylaminomethylen-acetessigsaeureethylester
  • diethyl isochelidonate

DownStream

Related Compounds

  • 5-Azaspiro[2.3]hexane-4-carboxylic acid
  • 3-Chloro-5-hydroxy-4-iodobenzonitrile
  • (S)-1-(4-Chloro-3-fluoropyridin-2-YL)ethan-1-amine hcl
  • 4-ethynyl-2,5-difluoro-N-methylaniline
  • [1-(2-Bromo-1,3-thiazol-4-yl)cyclobutyl]methanol
  • tert-butyl N-[5-(fluorosulfonyl)-2-hydroxy-3-methoxyphenyl]carbamate
  • (2R)-1-[1-(4-bromophenyl)cyclopropyl]propan-2-ol
  • (2R)-1-[1-(propan-2-yl)-1H-pyrazol-4-yl]propan-2-ol
  • 5-Methyl-4-(pyrrolidin-3-yloxy)-1,2-oxazole
  • 1-(1-Ethylcyclobutyl)-3-oxocyclobutane-1-carbonitrile
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