Prednisolone Sodium Phosphate

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Names

[ CAS No. ]:
125-02-0

[ Name ]:
Prednisolone Sodium Phosphate

[Synonym ]:
(11beta)
Phortisolone
disodium 2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl phosphate
Inflamase
prednisolon disodium phosphate
Prednisolone sodium phosphate
Optival
Predsol
Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, disodium salt, (11β)-
11b,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(Disodium phosphate)
Codelsol
Prednisolone (disodium phosphate)
prednisolone 21-disodium phosphate
Prednisolone 21-Phosphate Disodium Salt
MFCD07776968
11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(disodium phosphate)
phosphate de 2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-diméthyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodécahydro-3H-cyclopenta[a]phénanthrén-17-yl]-2-oxoéthyle de disodium
METRETON
Prozorin
Disodium Prednisolone 21-Phosphate
EINECS 204-722-9
Solucort
Dinatrium-2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethylphosphat
Predsolan
Prednesol
Dojilon
Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, sodium salt, (11β)- (1:2)
Disodium (11β)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate
Ak-pred

Chemical & Physical Properties

[ Boiling Point ]:
100 °C

[ Molecular Formula ]:
C21H27Na2O8P

[ Molecular Weight ]:
484.388

[ Flash Point ]:
361.9ºC

[ Exact Mass ]:
484.123901

[ PSA ]:
156.83000

[ LogP ]:
2.55100

[ Vapour Pressure ]:
4.17E-21mmHg at 25°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU4153300
CHEMICAL NAME :
Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-, 21-(dihydrogen phosphate), disodium salt
CAS REGISTRY NUMBER :
125-02-0
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C21-H27-O8-P.2Na
MOLECULAR WEIGHT :
484.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
360 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 22,1439,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5598 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 340 (estimated) No. of Female Employees: 180 (estimated)

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2937229000

Customs

[ HS Code ]: 2937229000

Related Compounds

  • prednisolone sodium phosphate
  • methylprednisolone sodium phosphate
  • Prednisolone sodium metazoate
  • Dexamethasone Sodium Phosphate EP Impurity H
  • Magnesium sodium phosphate (1:1:1)
  • Dexamethasone Sodium Phosphate
  • 3-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-3,3,3-trifluoropropanamido}hexanoic acid
  • (2R,3S)-3-(benzyloxy)-2-{[(1RS,5RS,6SR)-6-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)bicyclo[3.2.0]heptan-3-yl]formamido}butanoic acid
  • 2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylhexanamido]acetic acid
  • 2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methoxybutanoyl]-2-azabicyclo[2.1.1]hexane-5-carboxylic acid
  • 2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-methoxybutanamido]-4,4-difluorobutanoic acid
  • 2-{1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-dimethylpentanoyl]azetidin-3-yl}acetic acid
  • 2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-dimethyl-N-(prop-2-en-1-yl)pentanamido]acetic acid
  • 2-[(2S)-1-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]acetyl}piperidin-2-yl]acetic acid
  • 2-[(2S)-1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methoxy-2-methylpropanoyl]piperidin-2-yl]acetic acid
  • 3-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-propylpentanamido]propanoic acid
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