(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one
Suppliers
Names
[ CAS No. ]:
125-58-6
[ Name ]:
(6R)-6-(dimethylamino)-4,4-diphenylheptan-3-one
[Synonym ]:
Levothyl
Levadone
l-Polamivet
Polamivet
l-methadone
L-Polamidon
Levomethadone
Chemical & Physical Properties
[ Density]:
1.009g/cm3
[ Boiling Point ]:
423.7ºC at 760mmHg
[ Melting Point ]:
99-100ºC
[ Molecular Formula ]:
C21H27NO
[ Molecular Weight ]:
309.44500
[ Flash Point ]:
126.5ºC
[ Exact Mass ]:
309.20900
[ PSA ]:
20.31000
[ LogP ]:
4.29200
[ Vapour Pressure ]:
2.2E-07mmHg at 25°C
[ Index of Refraction ]:
1.538
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MJ5990000
- CHEMICAL NAME :
- 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, L-
- CAS REGISTRY NUMBER :
- 125-58-6
- BEILSTEIN REFERENCE NO. :
- 3213668
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C21-H27-N-O
- MOLECULAR WEIGHT :
- 309.49
- WISWESSER LINE NOTATION :
- 2VXR&R&1Y1&N1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 97 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 32 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 26500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 1600 ug/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - other effects on male
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - rat Testis
- DOSE/DURATION :
- 50 umol/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 27,123,1978
Safety Information
[ HS Code ]:
2922399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922399090
[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%