(4S)-4-amino-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-5-oxopentanoic acid

Names

[ CAS No. ]:
125780-86-1

[ Name ]:
(4S)-4-amino-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-5-oxopentanoic acid

[Synonym ]:
L-Glutamic acid,5.5'-ester with 3'-azido-3'-deoxythymidine
GluAZT
3'-Azido-5'-glutamyl-3'-deoxythymidine

Chemical & Physical Properties

[ Molecular Formula ]:
C15H20N6O7

[ Molecular Weight ]:
396.35500

[ Exact Mass ]:
396.13900

[ PSA ]:
203.72000

[ LogP ]:
0.11206

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (S)-5-(((2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) 1-tert-butyl 2-((tert-butoxycarbonyl)amino)pentanedioate
  • Zidovudine
  • Boc-Glu-OtBu

DownStream

Related Compounds

  • Tert-butyl 4-(4-amino-5-nitropyridin-2-yl)piperazine-1-carboxylate
  • Tert-butyl 4-(4,5-diaminopyridin-2-yl)piperazine-1-carboxylate
  • Benzyl 3-fluoro-4-oxoazocane-1-carboxylate
  • 2-(3-Benzyloxypropyl)pyridine
  • 4-(2-Bromoethoxy)thiane
  • (5S,9R)-tert-butyl 7-benzyl-9-(hydroxymethyl)-2,7-diazaspiro[4.4]nonane-2-carboxylate
  • 2-{[6-(Butan-2-yl)pyrimidin-4-yl]amino}ethan-1-ol
  • 7-Bromo-6-fluoro-3-methylbenzo[d]oxazol-2(3H)-one
  • 2-ethynyl-6-fluoro-5-methyl-1H-1,3-benzodiazole
  • 3-Cyclopropyloxolan-3-amine
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