(4S)-4-amino-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-5-oxopentanoic acid

Names

[ CAS No. ]:
125780-86-1

[ Name ]:
(4S)-4-amino-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-5-oxopentanoic acid

[Synonym ]:
L-Glutamic acid,5.5'-ester with 3'-azido-3'-deoxythymidine
GluAZT
3'-Azido-5'-glutamyl-3'-deoxythymidine

Chemical & Physical Properties

[ Molecular Formula ]:
C15H20N6O7

[ Molecular Weight ]:
396.35500

[ Exact Mass ]:
396.13900

[ PSA ]:
203.72000

[ LogP ]:
0.11206

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (S)-5-(((2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) 1-tert-butyl 2-((tert-butoxycarbonyl)amino)pentanedioate
  • Zidovudine
  • Boc-Glu-OtBu

DownStream

Related Compounds

  • 4-[4-(Cyclopropylmethyl)piperazin-1-yl]-3-(trifluoromethyl)aniline
  • 7-bromo-4-methoxy-2,3-dihydro-1H-indole
  • 4-{[(3-Methyloxetan-3-yl)methyl]amino}butanamide
  • 1-Acetyl-2-methylpyrrolidine-2-carboxylic acid
  • 5-amino-3-benzyl-1-methyl-1H-pyrazole-4-carbonitrile
  • ethyl 4-nitro-5-(trifluoromethyl)-1H-pyrazole-3-carboxylate
  • tert-butyl N-[3-[4-(trifluoromethyl)phenoxy]cyclobutyl]carbamate
  • 2-(6-Bromopyridine-3-carbonyl)-1,2,3,4-tetrahydroisoquinoline
  • 4-amino-2-methyl-N-thiazol-2-ylbenzamide
  • tert-Butyl N-[(2R,3S)-2-(aminomethyl)-1-[(2,4-dimethoxyphenyl)methyl]-4-oxo-azetidin-3-yl]carbamate
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