Pyrotinib

Names

[ CAS No. ]:
1269662-73-8

[ Name ]:
Pyrotinib

[Synonym ]:
2-Propenamide, N-[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-3-[(2R)-1-methyl-2-pyrrolidinyl]-, (2E)-
PYROTINIB
(2E)-N-(4-{[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino}-3-cyano-7-ethoxy-6-quinolinyl)-3-[(2R)-1-methyl-2-pyrrolidinyl]acrylamide

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
775.5±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C32H31ClN6O3

[ Molecular Weight ]:
583.080

[ Flash Point ]:
422.8±32.9 °C

[ Exact Mass ]:
582.214600

[ LogP ]:
5.64

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.677

[ Storage condition ]:
2-8℃

Related Compounds

  • Pyrotinib Racemate
  • Pyrotinib dimaleate
  • {3-[(Fluorosulfonyl)oxy]-4-methyl-5-(piperazin-1-yl)phenyl}methanesulfonyl fluoride
  • {3-[(Fluorosulfonyl)oxy]-2-methyl-5-(piperazin-1-yl)phenyl}methanesulfonyl fluoride
  • {5-[(Fluorosulfonyl)oxy]-2-methyl-3-(piperazin-1-yl)phenyl}methanesulfonyl fluoride
  • 3-[(Fluorosulfonyl)oxy]-2-methyl-5-[(piperazin-1-yl)methyl]benzene-1-sulfonyl fluoride
  • 5-[(Fluorosulfonyl)oxy]-2-methyl-3-[(piperazin-1-yl)methyl]benzene-1-sulfonyl fluoride
  • (9H-fluoren-9-yl)methyl 4-[3-(aminomethyl)-2,4,6-trimethyl-5-[2-(trimethylsilyl)ethynyl]phenyl]piperazine-1-carboxylate
  • (9H-fluoren-9-yl)methyl N-{2,4,6-trimethyl-3-[(piperazin-1-yl)methyl]-5-[2-(trimethylsilyl)ethynyl]phenyl}carbamate
  • (9H-fluoren-9-yl)methyl 4-({3-amino-2,4,6-trimethyl-5-[2-(trimethylsilyl)ethynyl]phenyl}methyl)piperazine-1-carboxylate
  • (9H-fluoren-9-yl)methyl 4-{3-[(fluorosulfonyl)oxy]-5-formyl-2,4,6-trimethylphenyl}piperazine-1-carboxylate
  • (9H-fluoren-9-yl)methyl N-{3-[(fluorosulfonyl)oxy]-2,4,6-trimethyl-5-[(piperazin-1-yl)methyl]phenyl}carbamate