sulfamerazine sodium

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Names

[ CAS No. ]:
127-58-2

[ Name ]:
sulfamerazine sodium

[Synonym ]:
EINECS 204-851-0
Sulfamerazin natrium
Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, sodium salt (1:1)
MFCD00068332
Sodium [(4-aminophenyl)sulfonyl](4-methyl-2-pyrimidinyl)azanide
2-Sulfanilamido-4-methylpyrimidine sodium salt
Solumedine
UNII-JOV4UJY07O
Solfamerazina sodica [DCIT]
Sodium sulfamerazine
sulfamerazine sodium
Soluble sulfamerazine
Sodium sulphamerazine
Sodium [(4-aminophenyl)sulfonyl](4-methylpyrimidin-2-yl)azanide
Sulfamerazine sodium salt
Sulfamerazine (sodium salt)

Chemical & Physical Properties

[ Boiling Point ]:
519.1ºC at 760mmHg

[ Melting Point ]:
216-219 °C

[ Molecular Formula ]:
C11H11N4NaO2S

[ Molecular Weight ]:
286.285

[ Flash Point ]:
267.8ºC

[ Exact Mass ]:
286.050049

[ PSA ]:
97.56000

[ LogP ]:
2.68880

[ Vapour Pressure ]:
7.03E-11mmHg at 25°C

[ Storage condition ]:
2-8℃

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WP0760000
CHEMICAL NAME :
Sulfanilamide, N(sup 1)-(4-methyl-2-pyrimidinyl)-, monosodium salt
CAS REGISTRY NUMBER :
127-58-2
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C11-H11-N4-O2-S.Na
MOLECULAR WEIGHT :
286.31
WISWESSER LINE NOTATION :
T6N CNJ BMSWR DZ& D1 &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,338,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1522 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,17,1944
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1739 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 81,17,1944
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,338,1953

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H332

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/22

[ Safety Phrases ]:
S7-S24-S45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3


Related Compounds

  • Sulfamerazine D4
  • iofensulfuron-sodium
  • potassium sodium 4,4'-bis(4-phenyl-2H-1,2,3-triazol-2-yl)stilbene-2,2'-disulphonate
  • NaBARF
  • Aminonaphtylsulphonate sodium
  • Potassium sodium nitrate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2,3-Dideoxy-4,5-O-(1-methylethylidene)-3-(nitromethyl)-L-threo-pentonic Acid Ethyl Ester
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • N-(6-methylbenzo[d]thiazol-2-yl)-3-(methylsulfonyl)-N-(pyridin-2-ylmethyl)benzamide